The Effect of Raddi (Anacardiaceae) Bark Extract on Histamine-Induced Paw Edema and Ileum Smooth Muscle Contraction.

Raddi (Anacardiaceae), popularly known as red aroeira, is used in traditional medicine to treat inflammatory, gastric, and respiratory disorders. The aim of this study was to evaluate the antihistaminic activity of bark extract by using in vivo and in vitro experimental models. The effects of were investigated on contractions induced by histamine, carbachol, and potassium chloride in isolated guinea pig ileum.