Context And Objective: Anencephaly is considered to be the most common type of neural tube defect. Our aim was to assess the clinical and gestational features of a cohort of fetuses with suspected anencephaly.
Design And Setting: Population-based retrospective cohort study in a referral hospital in southern Brazil.
Purpose: to correlate the clinical manifestations of patients with amenorrhea and X chromosome abnormalities.
Methods: a retrospective analysis of the clinical and laboratorial findings of patients with amenorrhea and abnormalities of X chromosome, attended between January 1975 and November 2007 was performed. Their anthropometric measures were evaluated through standard growth tables, and, when present, minor and major anomalies were noted.