Publications by authors named "Jamile de Oliveira Sa"
Cancer is a significant cause of death, precluding increasing life expectancy worldwide. That is a multifactorial disease initiated by intrinsic or extrinsic factors that induce cell differentiation into cancer cells. However, cancer development, progression, and metastasis are not controlled only by cancer cells.
View Article and Find Full Text PDFThe search for biomarkers associated with oral leukoplakia malignant transformation is critical for early diagnosis and improved prognosis of oral cancer patients. This systematic review and meta-analysis aimed to assess protein-based markers potentially associated with malignant transformation of oral leukoplakia. Five database and the grey literature were searched.
View Article and Find Full Text PDFArticle Synopsis
- * There is a pressing need for new biomarkers and therapeutic targets to improve clinical decision-making, with ongoing proteomic studies exploring the tumor environment and potential liquid biopsy sites for OSCC.
- * Although proteomics shows promise in identifying candidates for biomarkers and treatments, these targets have not yet made it into clinical practice, indicating the need for better experimental designs and translation of research into actionable clinical strategies.