Publications by authors named "Jamil Antonio Cedeno"

Background: Acute Respiratory Distress Syndrome (ARDS) necessitates personalized treatment strategies due to its heterogeneity, aiming to mitigate Ventilator-Induced Lung Injury (VILI). Advanced monitoring techniques, including imaging, driving pressure, transpulmonary pressure, and mechanical power, present potential avenues for tailored interventions.

Objective: To review some of the most important techniques for achieving greater personalization of mechanical ventilation in ARDS patients as evaluated in randomized clinical trials, by analyzing their effect on three clinically relevant aspects: mortality, ventilator-free days, and gas exchange.

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Article Synopsis
  • Low levels of anti-SARS-CoV-2 S antibodies in critically ill COVID-19 patients are linked to higher mortality rates and suggest that these antibodies play a protective role.
  • The study involved 92 ICU patients and showed that absence of these antibodies coincided with increased viral RNA in plasma and higher rates of N-antigenaemia.
  • The findings indicate that monitoring antibody levels could be crucial for understanding patient outcomes and managing severe COVID-19 cases effectively.
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Background: COVID-19 can course with respiratory and extrapulmonary disease. SARS-CoV-2 RNA is detected in respiratory samples but also in blood, stool and urine. Severe COVID-19 is characterized by a dysregulated host response to this virus.

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