The use of genomic assays reduces rates of chemotherapy: a single-institution experience.

Introduction: The National Institute for Clinical Excellence recommends the use of tumour profiling tests to guide adjuvant chemotherapy in breast cancer. The Oncotype DX™ score (Genomic Health) has superseded more traditional tools such as PREDICT in appropriate patients (ER + ve, HER2-ve, lymph node negative and with a Nottingham Prognostic Index [NPI] ≥ 3.4).

The Outcome of Anticoagulation on Endovenous Laser Therapy for Superficial Venous Incompetence.

Objectives: The purpose of this study was to evaluate whether anticoagulation (warfarin or direct oral inhibitors) affected the success of endovenous treatment.

Methods: Patients taking anticoagulation (warfarin or direct oral inhibitors) undergoing endovenous treatment in the form of endovenous laser ablation (EVLA) were matched against controls for sex, age, leg, and vein. Data were collected prospectively between January 2012 and March 2017.

A double aortic arch presenting in the 7th decade of life.

A 64-year-old woman presented to the Vascular Outpatient department concerned about a pulsatile swelling in her right supraclavicular fossa. She had no other symptoms. A computed tomography angiogram demonstrated a double aortic arch (DAA) with the innominate artery arising from the right arch and left common carotid and subclavian arteries arising from the left arch.