Majority of Fortune 500 Companies in 2018 Did Not Recognize Risk of Epidemics Such as COVID-19.

Infectious disease threats, like the 2002 severe acute respiratory syndrome coronavirus (SARS-CoV) disease, 2009 pandemic influenza A (H1N1), and the current coronavirus disease 2019 (COVID-19), pose multisectoral risk with the potential for wide-ranging socioeconomic disruption. In our globally intertwined economy, the impact of such events can elicit economic shock waves that reach far beyond the country of origin. Review of the 2018 Fortune 500 company 10-K filings shows the majority did not document perceived risks associated with epidemics, outbreaks, or pandemics.

An anthropomorphic breast model for breast imaging simulation and optimization.

Rationale And Objectives: Optimization studies for x-ray-based breast imaging systems using computer simulation can greatly benefit from a phantom capable of modeling varying anatomical variability across different patients. This study aimed to develop a three-dimensional phantom model with realistic and randomizable anatomical features.

Materials And Methods: A voxelized breast model was developed consisting of an outer layer of skin and subcutaneous fat, a mixture of glandular and adipose, stochastically generated ductal trees, masses, and microcalcifications.