A moderate dose of pseudoephedrine does not alter muscle contraction strength or anaerobic power.

Objective: To investigate the effect of an acute oral administration of pseudoephedrine (PSE) on muscle function, fatigue, and anaerobic power output.

Design And Materials: Healthy males (N = 10) and females (N = 10) were allocated to receive both a placebo and PSE (120 mg) using a randomized, double-blind, crossover experimental design. Each subject had their maximal voluntary contraction strength and fatigability measured for both handgrip and ankle dorsi-flexion.