Publications by authors named "Jamie R F Wilson"
Article Synopsis
- The study examines six cases of perioperative spinal cord injury (SCI) that occurred during complex adult deformity surgeries, noting their causes, treatments, and outcomes.
- Out of 272 patients from the Scoli-RISK-1 cohort study, 2.2% experienced SCI, with cases occurring both during and after surgery.
- The findings highlight the importance of close postoperative monitoring and timely intervention to prevent lasting neurological damage.
Article Synopsis
- The study aimed to investigate how the level of frailty influences long-term neurological and functional outcomes in patients who underwent surgery for degenerative cervical myelopathy (DCM).
- Researchers analyzed data from 757 patients categorized into four frailty groups (not frail, pre-frail, frail, severely frail) and assessed functional and quality of life outcomes before and two years post-surgery.
- While more frail patients had significantly lower initial functional scores, the improvement in scores over two years did not significantly differ among the frailty groups, indicating similar recovery potential regardless of frailty level.
Article Synopsis
- The use of methylprednisolone (MP) for treating acute traumatic spinal cord injury (ATSCI) is debated, prompting the creation of a new pooled data set based on past studies (NASCIS2 and Sygen) to re-evaluate MP's effectiveness.
- The new data set excluded patients based on specific criteria, totaling 31.6% fewer patients compared to the original NASCIS2 study, and classified injuries into five severity cohorts, revealing varying recovery outcomes.
- While the updated data showed some positive effects of MP on recovery in certain subgroups, modern statistical methods suggest that these results might be random and clinically insignificant, prompting further investigation into the drug's true effectiveness.*
Study Design: Literature Review (Narrative).
Objective: To introduce the number one research priority for Degenerative Cervical Myelopathy (DCM): Raising Awareness.
Methods: Raising awareness has been recognized by AO Spine RECODE-DCM as the number one research priority.
Article Synopsis
- The study is a narrative review focusing on the need for clear diagnostic criteria for Degenerative Cervical Myelopathy (DCM), which is crucial for timely diagnosis and treatment.
- DCM leads to chronic spinal cord dysfunction and neurological decline, making early recognition and surgical intervention essential to enhance patient quality of life.
- Currently, there are no standardized diagnostic criteria for DCM, resulting in frequent delays in diagnosis, which hinder effective treatment and recovery for patients.
Background Context: Traditionally, a nonoperative approach has been favored for elderly patients with lumbar spondylolisthesis due to a perceived higher risk of morbidity with surgery. However, most studies have used an arbitrary age cut-off to define "elderly" and this research has yielded conflicting results.
Purpose: The purpose of this study was to investigate the impact of frailty on morbidity after surgery for degenerative lumbar spondylolisthesis treated with a posterior approach.
Background: With an aging population, there are an increasing number of elderly patients undergoing spine surgery. Recent literature in other surgical specialties suggest frailty to be an important predictor of outcomes.
Purpose: The aim of this review was to examine the association between frailty and outcomes after spine surgery.
Study Design: Prospective cross-sectional blinded-assessor cohort study.
Objective: The aim of this study was to determine the inter-rater reliability of the modified Japanese Orthopaedic Association (mJOA) score in a large cohort of degenerative cervical myelopathy (DCM) patients.
Summary Of Background Data: The mJOA score is widely accepted as the primary outcome measure in DCM; it has been utilized in clinical practice guidelines and directly influences treatment recommendations, but its reliability has not been established.
Study Design: Retrospective analysis of data from the National Surgical Quality Improvement Program (NSQIP).
Objective: We sought to compare the short-term outcomes of laminectomy with/without fusion for single-level lumbar degenerative spondylolisthesis (DS).
Summary Of Background Data: Lumbar DS is a common cause of low back and radicular pain.
Article Synopsis
- Frailty, measured by the modified frailty index (MFI), is a better predictor of adverse surgical outcomes in patients with Degenerative Cervical Myelopathy (DCM) than age alone.
- The study analyzed data from over 41,000 DCM patients, finding that frailty significantly increases the risk of complications, longer hospital stays, and non-home discharges post-surgery.
- The MFI-5 index demonstrated strong predictive accuracy and is nearly equivalent to the MFI-11, suggesting it is a valuable tool for clinicians in assessing surgical risk in DCM patients.
Previous studies aimed at identifying predictors of clinical outcomes following surgical decompression for degenerative cervical myelopathy (DCM) are limited by multicollinearity among predictors, whereby the high degree of correlation between covariates precludes detection of potentially significant findings. We apply partial least squares (PLS), a data-driven approach, to model multi-dimensional variance and dissociate patient phenotypes associated with functional, disability, and quality of life (QOL) outcomes in DCM. This was a post-hoc analysis of DCM patients enrolled in the prospective, multi-center AOSpine CSM-NA/CSM-I studies.
View Article and Find Full Text PDFArticle Synopsis
- Degenerative cervical myelopathy (DCM) is a common condition that seriously affects various aspects of health, and a multidisciplinary care approach is recommended to best meet patient needs.
- The article outlines the significance of teamwork across different medical disciplines in managing DCM at all stages, from assessment to postoperative care.
- A successful treatment plan for DCM patients requires collaboration among various healthcare professionals, including surgeons, neurologists, therapists, and social workers, to provide personalized and effective care.
Article Synopsis
- - The study focuses on degenerative cervical myelopathy (DCM), a leading cause of spinal cord dysfunction in adults, and compares the safety and effectiveness of three surgical options: anterior cervical discectomy and fusion (ACDF), anterior cervical corpectomy and fusion (ACCF), and a hybrid approach combining both techniques.
- - Researchers analyzed data from 1,298 patients who underwent these surgeries between 2012 and 2017, examining outcomes like mortality, complications, reoperations, and hospital stays using statistical methods to compare each procedure.
- - Results showed no significant differences in short-term outcomes like mortality and readmission between the surgical methods; however, ACCF had a higher risk of major complications compared to AC
Study Design: Case report (level IV evidence).
Objective: To describe a potential novel application of hyperbaric oxygen therapy (HBOT) in the successful treatment of a postoperative spinal cord injury.
Summary Of Background Data: A 68-year-old man presented with an acute spinal cord injury (ASIA impairment scale D), on the background of degenerative lower thoracic and lumbar canal stenosis.
Study Design: Review article.
Objectives: A narrative review of the literature on the current advances and limitations in quality and safety improvement initiatives in spine surgery.
Methods: A comprehensive literature search was performed using Ovid MEDLINE focusing on 3 preidentified concepts: (1) quality and safety improvement, (2) reporting of outcomes and adverse events, and (3) prediction model and practice guidelines.
Study Design: Narrative review.
Objective: To summarize relevant studies regarding the utilization of intraoperative neurophysiological monitoring (IONM) techniques in spine surgery implemented in recent years.
Methods: A literature search of the Medline database was performed.
Machine learning represents a promising frontier in epidemiological research on spine surgery. It consists of a series of algorithms that determines relationships between data. Machine learning maintains numerous advantages over conventional regression techniques, such as a reduced requirement for a priori knowledge on predictors and better ability to manage large datasets.
View Article and Find Full Text PDFBackground: Degenerative spondylolisthesis (DS) is often treated with lumbar spinal fusion (LSF). However, there is concern that the morbidity of LSF may be prohibitively high in older adults.
Objective: To evaluate the impact of advanced age on the safety of LSF for DS.
Background: The effect on functional and quality of life (QOL) outcomes of surgery in elderly degenerative cervical myelopathy (DCM) patients has not been definitively established.
Objective: To evaluate the effect of older age on the functional and QOL outcomes after surgery in an international, multi-center cohort of patients with DCM.
Methods: 107 patients aged over 70 years old (mean 75.
Comparison of the Inpatient Complications and Health Care Costs of Anterior versus Posterior Cervical Decompression and Fusion in Patients with Multilevel Degenerative Cervical Myelopathy: A Retrospective Propensity Score-Matched Analysis.
World Neurosurg
February 2020
Background: The optimal surgical approach for multilevel degenerative cervical myelopathy (DCM) is unclear, and there is significant variation in practice patterns. We sought to compare inpatient complications and costs of anterior (ACDF) versus posterior cervical decompression and fusion (PCDF).
Methods: Patients who underwent multilevel ACDF or PCDF for DCM were identified from the National Inpatient Sample for 2004-2014 using ICD-9-CM codes.
Article Synopsis
- The understanding of degenerative cervical myelopathy (DCM) has advanced significantly in the last two decades, leading to improved assessment and diagnosis.
- New technologies, like multiparametric MRI and biomarkers, are being explored to objectively measure DCM severity.
- Innovations in pharmacological treatments and less invasive surgical techniques aim to enhance patient outcomes and the accuracy of diagnosis in future DCM management.
Study Design: Post-hoc analysis of a prospective, multicenter cohort study.
Objective: To analyze the impact of smoking on rates of postoperative adverse events (AEs) in patients undergoing high-risk adult spine deformity surgery.
Summary Of Background Data: Smoking is a known predictor of medical complications after adult deformity surgery, but the effect on complications, implant failure and other AEs has not been adequately described in prospective studies.
Study Design: Technical report.
Objective: This article describes the technique of using intraoperative sigmoidoscopy as an adjunct for retrieval of the AxiaLIF lumbosacral screw after failure of lumbar fusion.
Summary Of Background Data: Minimally invasive axial lumbar interbody fusion devices have emerged during the past 3 years as an alternative to traditional surgery for the treatment of intractable back pain.