Publications by authors named "Jamie Mosher"
Glioblastoma (GB) is a deadly and aggressive cancer of the CNS. Even with extensive resection and chemoradiotherapy, patient survival is still only 15 months. To maintain growth and proliferation, cancer cells require a high oxidative state.
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- Patients in rural areas of New Zealand with acute appendicitis have worse surgical outcomes compared to those in metropolitan centers, largely due to longer wait times.
- A study analyzed data from 3533 appendicectomy cases between 2014 and 2019, revealing that rural patients faced significantly delayed treatment (20.8 hours) when transferred to urban hospitals versus quicker care (7.6 hours) at regional centers.
- Higher perforation rates (31%) and complications (20%) were observed in patients who were transferred compared to those treated in metropolitan (20% perforation, 17% complication) and regional centers (17% perforation, 10% complication).
Article Synopsis
- * Our research showed that we could effectively deliver the HIV peptide to DCs and stimulate the proliferation of certain immune cells, though we did not see signs of activation in B or T lymphocytes, which are crucial for a strong immune response.
- * The approach of delivering peptide antigens to DCs looks promising for developing an HIV vaccine, but further research is needed, particularly in delivering multiple peptides simultaneously from different viral proteins to enhance the immune response.