Halofuginone- and chitosan-coated amnion membranes demonstrate improved abdominal adhesion prevention.

Our objective was to determine whether coating the amniotic membrane with halofuginone, a type 1 collagen synthase inhibitor, with or without the hemostasis-inducing substance chitosan, reduced the number and severity of adhesions in the rat uterine horn injury model. Sixty retired breeder Sprague-Dawley rats underwent midline laparotomy and a zone of ischemia was created in the left uterine horn of each animal. Rats were randomized to one of six treatment groups: (1) untreated control, (2) oxidized regenerated cellulose (Interceed®) (ORC), (3) plain amnion, (4) amnion coated on both sides with 0.

Robotic-assisted laparoscopic ovarian tissue transplantation.

Objective: To describe a technique for frozen-banked ovarian tissue transplantation using robotic-assisted laparoscopy.

Design: Case study.

Setting: Academic tertiary care center.