Integration of AI-Generated Images in Clinical Otolaryngology.

Recent advances in generative artificial intelligence (AI) have enabled remarkable capabilities in generating images, audio, and videos from textual descriptions. Tools like and can produce striking visualizations from simple prompts, while services like and can generate short video clips. These technologies offer intriguing possibilities for clinical and educational applications in otolaryngology.

Geniculate ganglion diverticulum: a potential imaging marker in patients with idiopathic intracranial hypertension.

Purpose: The diagnosis of idiopathic intracranial hypertension (IIH) is often challenging in patients who do not present with classic symptoms. Brain MRI can play a pivotal role, as several imaging findings, such as an empty sella appearance (ESA), have been shown to be associated with IIH. Yet, none of the MRI signs have been shown to have a high sensitivity and specificity.

Trends of female authorship in head and neck surgery publications over the last decade.

Background: While other otolaryngology subspecialties have established female authorship trends, there is no comprehensive study within head and neck surgery (HNS).

Methods: Five researchers recorded the gender identity of first and senior authors from HNS subspecialty papers (head and neck oncology, endocrine surgery, salivary gland pathology, and microsurgery) derived from 10 journals in otolaryngology and oncology in the years 2013, 2016, 2019, and 2022.

Results: From 3457 articles, 6901 unique author identities were analyzed.

The Isolation and Characterization of a Broad Host Range Bcep22-like Podovirus JC1.

Bacteriophage JC1 is a phage with a C1 morphotype, isolated on host strain Van1. Phage JC1 is capable of infecting an expansive range of complex (Bcc) species. The JC1 genome exhibits significant similarity and synteny to Bcep22-like phages and to many phages.

Mayaro Virus Non-Structural Protein 2 Circumvents the Induction of Interferon in Part by Depleting Host Transcription Initiation Factor IIE Subunit 2.

Mayaro virus (MAYV) is an emerging mosquito-transmitted virus that belongs to the genus within the family . Humans infected with MAYV often develop chronic and debilitating arthralgia and myalgia. The virus is primarily maintained via a sylvatic cycle, but it has the potential to adapt to urban settings, which could lead to large outbreaks.

SARS-CoV-2 Nonstructural Protein 1 Inhibits the Interferon Response by Causing Depletion of Key Host Signaling Factors.

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the causative agent of the ongoing coronavirus disease 2019 (COVID-19) pandemic. While previous studies have shown that several SARS-CoV-2 proteins can antagonize the interferon (IFN) response, some of the mechanisms by which they do so are not well understood. In this study, we describe two novel mechanisms by which SARS-CoV-2 blocks the IFN pathway.