Publications by authors named "Jamie C Ye"

Most cancer deaths result from progression of therapy resistant disease, yet our understanding of this phenotype is limited. Cancer therapies generate stress signals that act upon mitochondria to initiate apoptosis. Mitochondria isolated from neuroblastoma cells were exposed to tBid or Bim, death effectors activated by therapeutic stress.

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Article Synopsis
  • * Researchers found that two types of dendritic cells significantly impact how well a person responds to the HBV vaccine, depending on their baseline state before vaccination.
  • * By analyzing gene expression in these dendritic cell subsets and using machine learning, they developed models that can better predict how effective a vaccine will be for different individuals based on their pre-vaccination immune cell characteristics.
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