Review of F-Fluciclovine PET for Detection of Recurrent Prostate Cancer.

Fluorine 18 (F) fluciclovine (anti-1-amino-3-F-fluorocyclobutane-1-carboxylic acid [FACBC]) is a radiolabeled amino acid analog that takes advantage of the amino acid transport upregulation in several types of cancer cells. FACBC is taken up to a greater extent in prostate cancer cells than in surrounding normal tissue, providing an opportunity for its use in cases of this common cancer. In 2016, the U.