Incidental prostate-specific membrane antigen-avid glioblastoma detected on Ga-prostate-specific membrane antigen PET/CT.

A 74-year-old man was referred for a Ga-prostate-specific membrane antigen (PSMA) PET/CT scan for newly diagnosed prostate cancer which confirmed the presence of PSMA avid cancer in the right gland with no evidence of PSMA metastasis. Incidentally, there was a markedly PSMA avid (SUVmax 7.0) lobulated periventricular mass in the region of the left basal ganglia which was T2 hyperintense and T1 hypointense with perilesional oedema and vivid Gadolinium enhancement on MRI.

A rare case of urachal mucinous adenocarcinoma detected by 18F-FDG PET/CT and MRI.

Urachal adenocarcinomas are rare cancers of the urinary bladder. Both CT and MRI are useful imaging modalities for the diagnosis and evaluation of urachal adenocarcinoma. Unlike CT or MR, there have been variable FDG PET findings with urachal tumours potentially due to considerable variation in their hypermetabolism.

Steroid responsive inflammatory myofibroblastic tumor of the lung evaluated by FDG PET/CT imaging.

A 68-year-old gentleman was referred for F-FDG PET/CT for a pulmonary mass in the left upper lobe which demonstrated intensely FDG-avid confluent pulmonary consolidation in the left upper lobe (SUV 15.1). Histopathologic biopsy of the left upper lobe lung mass was consistent with inflammatory myofibroblastic tumor (IMT).

Incidental Intrahepatic Hepatocellular Cholangiocarcinoma Detected on 68Ga-PSMA PET/CT.

A 69-year-old man with intermediate-risk prostate cancer and a mildly elevated prostate-specific antigen of 8.2 μg/L was referred for 68Ga-prostate-specific membrane antigen (68Ga-PSMA) PET/CT for primary staging. An incidental intensely 68Ga-PSMA-avid hepatic focus was seen on PSMA PET and subsequent FDG PET/CT and MRI cholangiogram.

Disseminated sarcoidosis involving lymph nodes, bone and spleen with progressive cardiac sarcoidosis on F-FDG PET/CT and cardiac MRI.

A 63-year-old lady with a background of ischemic heart disease was referred for F-FDG PET/CT for multiple lytic bone lesions which showed disseminated FDG avid lesions in the skeleton, nodal stations as well as spleen simulating advanced malignancy such as diffuse lymphomatous disease. A diagnosis of sarcoidosis was pathologically confirmed with bone biopsy. Following treatment, repeat PET/CT revealed significant regression of FDG avid lesions, however prominent uptake in the lateral ventricular wall was suspicious for active cardiac sarcoidosis, particularly given recurrent chest pain.

Atypical metastatic lung cancer of the right ventricle on FDG PET/CT.

Although primary cardiac tumours are extremely uncommon, secondary tumours or cardiac metastasis are not. We present a 68-year-old gentleman with squamous cell carcinoma of the right lower lobe with bony metastasis to the right clavicle who was treated with radiotherapy to the lung and clavicle as well as combination immunotherapy (Pembrolizumab) and chemotherapy (Carboplatin/Paclitaxel). Despite completing the above treatment regime, F-FDG PET/CT scan showed progression with two new sites of metastasis including a focus in the lateral wall of the right ventricle which correlate to a soft tissue density mass on CT as well as a FDG avid mass in the left masseter.

Synchronous Recurrence of Metachronous Lung Cancer and Hodgkin Lymphoma Within an Axillary Lymph Node Isolated on 18F-FDG PET/CT.

An 82-year-old man with a background of non-Hodgkin lymphoma in remission, resected left lower lobe adenocarcinoma (stage IA), and resected cutaneous melanoma of the left forearm more than 5 years prior presented with cerebral metastatic disease. Excision biopsy confirmed adenocarcinoma of lung origin. Further evaluation with 18F-FDG PET/CT demonstrated FDG-avid disease in the right thorax, axilla, and lower neck and isolated cutaneous uptake in the right forearm.

Incidental prostate-specific membrane antigen-avid meningioma detected on Ga-prostate-specific membrane antigen PET/CT.

A 70-year-old gentleman with a history of Gleason score 7 (3 + 4) prostate adenocarcinoma was treated with radical prostatectomy with clear surgical margins. Postoperatively his prostate specific antigen was undetectable. However, his prostate specific antigen was slowly rising and he was referred for a Galium-Prostate Specific Membrane Antigen (PSMA) PET/CT scan.

Variability of Central Corneal Thickness Measurements-Comparing Zeiss IOL Master and Tomey Corneal Specular Microscope.

Purpose: The aim of this study was to compare the intraobserver repeatability and agreement of central corneal thickness (CCT) measurements by 2 commonly available instruments, Zeiss IOL Master 700 (SS-OCT-based optical biometry device) and Tomey corneal specular microscope EM-3000 (Noncontact specular microscopy).

Design: Retrospective study.

Methods: This is a retrospective analysis of data from routine clinical practice in which preoperative CCT measurements of 105 patients scheduled for cataract surgery were analyzed.