Publications by authors named "James Yu Lin"
Article Synopsis
- Hepatocellular carcinoma (HCC) is a serious liver cancer that can grow and spread quickly.
- Researchers studied a protein called NPRL2, which is part of a group called GATOR1 that helps control tumor growth in HCC.
- They found that reducing NPRL2 levels made the cancer cells grow faster and worse, showing that NPRL2 is important for improving the understanding and treatment of this type of cancer.
Importance: The role of heavy alcohol intake, aldehyde dehydrogenase 2 gene (ALDH2) rs671 polymorphism, and hepatitis B virus (HBV) infection in hepatocellular carcinoma (HCC) development and mortality remains uncertain.
Objective: To investigate the association of heavy alcohol intake, ALDH2 rs671 polymorphism, and HBV infection with HCC development and mortality in patients with cirrhosis.
Design, Setting, And Participants: This retrospective cohort study enrolled patients with cirrhosis with heavy alcoholism or/and HBV infection from January 2005 to December 2020.