Publications by authors named "James William Dodd"
Rationale: Lung function in early adulthood is associated with subsequent adverse health outcomes.
Objectives: To ascertain whether stable and reproducible lung function trajectories can be derived in different populations and investigate their association with objective measures of cardiovascular structure and function.
Methods: Using latent profile modelling, we studied three population-based birth cohorts with repeat spirometry data from childhood into early adulthood to identify trajectories of forced expiratory volume in 1 s (FEV)/forced vital capacity (FVC).
Article Synopsis
- After puberty, females are more prone to developing severe asthma than males, influenced by various complex factors.
- A study analyzed data from two databases, showing that while women with severe asthma tended to report more symptoms and higher obesity rates, they also demonstrated better lung function (FEV%) and lower levels of certain asthma-related biomarkers compared to men.
- The findings suggest significant gender differences in asthma presentation and treatment, highlighting the need for tailored approaches to management in females.
Introduction: continuous positive airway pressure (CPAP) and high-flow nasal oxygen (HFNO) provide enhanced oxygen delivery and respiratory support for patients with severe COVID-19. CPAP and HFNO are currently designated as aerosol-generating procedures despite limited high-quality experimental data. We aimed to characterise aerosol emission from HFNO and CPAP and compare with breathing, speaking and coughing.
View Article and Find Full Text PDFPulmonary function tests are fundamental to the diagnosis and monitoring of respiratory diseases. There is uncertainty around whether potentially infectious aerosols are produced during testing and there are limited data on mitigation strategies to reduce risk to staff. Healthy volunteers and patients with lung disease underwent standardised spirometry, peak flow and FE assessments.
View Article and Find Full Text PDFThe longer-term consequences of SARS-CoV-2 infection are uncertain. Consecutive patients hospitalised with COVID-19 were prospectively recruited to this observational study (n=163). At 8-12 weeks postadmission, survivors were invited to a systematic clinical follow-up.
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