Publications by authors named "James Wilfred Navalta"

Purpose: To evaluate the risk of sarcopenia on the length of hospital stay and deaths in preoperative cancer patients as well its relation to physical and functional capacity.

Methods: Preoperative patients admitted to the Cancer Hospital of Mato Grosso comprised the sample. Sociodemographic data, lifestyle data, and a questionnaire for sarcopenia screening were collected.

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Objectives: The aim of this study was to analyze the effects of intermittent fasting (IF) on the performance of rats subjected to resistance training ladder climbs (RTLCs).

Methods: Thirty-two Wistar rats (80-d-old) were placed into one of the following four groups (n = 8/group): control (C), which were fed a standard diet with no exercise; intermittent fasting (IF) rats underwent IF for 16 h/d, fed a standard diet for a period of 8 h/d with no exercise; trained control (TC) were fed a standard diet and submitted to RTLC; and trained intermittent fasting (TIF) underwent IF for 16 h/d, fed a standard diet for a period of 8 h/d, and submitted to RTLC. Training groups completed 6-wk of RTLC (3 × /wk).

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Article Synopsis
  • The study examined the effects of high-fat (HF: 45% fat) and very high-fat (VHF: 60% fat) diets combined with a fructose drink on rats, comparing them to a control group on a lower-fat diet for 70 days.
  • Results indicated that the HF diet caused greater weight gain, adipose tissue increases, and metabolic issues (like hyperinsulinemia) compared to both VHF and control groups.
  • The findings suggest that a 45% fat diet with added sugars might more accurately replicate human obesity, challenging the assumption that higher fat intake is always worse and offering insights for better obesity treatment guidelines.
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Background: Repeated measures analysis of covariance and three-way analysis of variance with repeated measures are common statistical methods. For a valid interpretation of blood pressure (BP) response to exercise, a variety of additional statistical methods must be implemented. Four additional statistical methods are presented: technical error of measurement (SEM), smallest real difference (SRD), magnitude-based inference and mixed effect modeling technique (MEM).

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  • The study assessed the impacts of combined resistance and aerobic training (RT+AT) on bone mineral density (BMD) and physical performance in individuals living with HIV (PLWH).
  • A total of 40 participants were split into two groups: one receiving RT+AT training three times a week for six months, and a control group maintaining their usual lifestyle.
  • Results showed significant improvements in BMD, lean body mass, inflammation markers, and physical capabilities like handgrip strength and gait speed in the RT+AT group compared to the control group.
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  • The study examined whether a high protein diet using isolated whey protein (IWP) and strength training could enhance performance and reduce body fat in male Wistar rats without causing health issues.
  • Four groups of rats were tested: two with normal protein diets (14% IWP) and two with a high protein diet (35% IWP), with half of each group undergoing strength training.
  • Results showed that the high protein trained group significantly improved performance and muscle mass compared to other groups, and no harmful effects on health were observed, indicating a potential benefit for minimizing the risk of metabolic disorders.
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Purpose: This study aimed to verify the effect of 6 months of periodized resistance training (RT) with and without blood flow restriction (BFR) in patients with stage 2 chronic kidney disease (CKD) on glomerular filtration rate (GFR), uremic parameters, cytokines, and klotho-fibroblast growth factor 23 (FGF23) axis.

Methods: A total of 105 subjects were randomized in three groups of 35 each: control (CTL), RT, and RT + BFR. A first visit was required for an anamnesis to evaluate the number of medications and anthropometric measurements (body weight, height, and body mass index).

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Purpose: Relative handgrip strength (RHGS), Aged Based on Exercise Stress Testing (A-BEST), and chronological age were evaluated as predictors of impaired mobility in older women.

Methods: Participants included 88 older women (mean age 68.13±6.

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Footpod monitors are wearable devices attaching to the shoe with the ability to sense oscillations in leg movement; however, few studies provide reliability. The purpose was to provide reliability data for outdoor tasks as measured by the Stryd Power Meter, which is a footpod monitor. Young healthy individuals (N=20, male n=12, female n=8) completed two 5-min self-paced walks along a trail, and two 5-min trail runs.

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Context: Increasing physical activity and promoting healthy behaviors may play a key role in reducing the adverse effects of antiretroviral therapy and HIV.

Objective: This study investigated the effects of an 8-week lifestyle modification program (LMP) on quality of life, anthropometric characteristics and CD4+T cell count of people living with HIV (PLWH).

Methods: Thirty PLWH taking ART were randomly assigned to a lifestyle modification program (LMP) (n = 15) or standard care control (CON) group (n = 15).

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Objectives: Isolated whey protein (IWP) can decrease body fat compared with other protein sources. The present study verified the effects of high protein diet (HD) containing IWP on several parameters of rats subjected to resistance training (RT).

Methods: Thirty-two male Wistar rats (60 days of age) were separated into four groups (n = 8/group): sedentary normoproteic (IWP 14%; SN); sedentary hyperproteic (IWP 35%; SH); trained normoproteic (IWP 14%; TN), and trained hyperproteic (WPI 35%; TH).

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Background: Surfactant protein D (SP-D) is a member of the collectin family and is an important component of the pulmonary innate host defense. To find the relationship between exercise training and SP-D in diabetes, we examined the possible effects of a 10-week endurance exercise-training program on serum levels of SP-D, leptin, lipid profile and insulin resistance in obese women with type-2 diabetes (T2DM).

Methods: Twenty-two obese women with T2DM were randomly assigned to either exercise training (ET) or control (C) group.

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Purpose: Although there is limited evidence regarding the pathophysiological effects of a high-protein diet (HD), it is believed that this type of diet could overload the body and cause damage to the organs directly involved with protein metabolism and excretion. The aim of this study was to verify the effects of HD on biochemical and morphological parameters of rats that completed a resistance training protocol (RT; aquatic jump) for 8 weeks.

Methods: Thirty-two adult male Wistar rats were divided into four groups (n = 8 for each group): sedentary normal protein diet (SN-14%), sedentary high-protein diet (SH-35%), trained normal protein diet (TN-14%), and trained high-protein diet (TH-35%).

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The aim of this study was to investigate the effects of different resistance training (RT) volumes on MMP activity in skeletal muscle, visceral adipose tissue and circulation. 21 Wistar rats were randomly divided into 3 groups (n=7 per group): sedentary control (SC); RT with 4 ladder climbs (RT-4; 50, 75, 90 and 100% of their maximal carrying capacity) and RT with 8 ladder climbs (RT-8 with 2 sets for each load). The 8-week RT consisted of climbing a 1.

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Cardiotonic drugs and exercise training promote cardiac inotropic effects, which may affect training-induced cardiac adaptations. This study investigated the effects of long-term administration of digoxin on heart structure and function, and physical performance of rats submitted to high-intensity interval training (HIIT). Male Wistar rats, 60 days old, were divided into control (C), digoxin (DIGO), trained (T), and trained with digoxin (TDIGO).

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Background: Deregulation of glycemic and glycated hemoglobin (HbA1) levels accelerate the progression of cardiovascular complications in type 1 diabetes mellitus (T1DM). The aim of this study was to investigate the association between HbA1 and changes in blood pressure of children and adolescents with T1DM.

Methods: A total of 60 children and adolescents were recruited and allocated into two groups (prehypertension and control group).

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This study was designed to compare the effects of linear periodization (LP) and undulating periodization (UP) on functional capacity, neuromuscular function, body composition, and cytokines in elderly sedentary women. We also aimed to identify the presence of high responders (HR), medium responders (MR), and low responders (LR) for irisin, interleukin-1 beta (IL-1β), toll-like receptor-4 (TLR-4), and brain-derived neurotrophic factor (BDNF) to resistance training (RT). Forty-nine elderly women were assigned to a control group, LP, and UP scheme.

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The association of ageing with obesity commits elderly women and has been correlated with multiple degenerative processes, which could be occasioned by an enhancing in levels of matrix metalloproteinase-2 and metalloproteinase-9 (MMPs) as well by an cytokine unbalance that included an enhancing on interleukin-6 (IL-6). Furthermore, other factors could be also related to degenerative process, as they could be reduced by eccentric resistance exercise (ERE), which seems particularly important to initiate resistance training in obese older adults. In this view, this study aims to determinate the effects of an acute ERE session on serum MMP-2, MMP-9 and IL-6 in elderly obese women.

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These data describe the effects of combined aerobic plus resistance training (CT) with regards to risk factors of metabolic syndrome (MetS), quality of life, functional capacity, and pro- and anti-inflammatory cytokines in women with MetS. In this context, thirteen women (35.4 ± 6.

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Background: Matrix metalloproteinases (MMPs) are a major group of enzymes that play essential roles in normal functioning of diverse tissues during growth, development, and aging. However, among the MMPs little is known regarding the role of exercise in MMP-9 and MMP-2 function in humans.

Objective: The aim of this study was to provide a systematic comprehensive review of the literature examining the effect of different exercise interventions on MMP-9 and MMP-2 in human investigations.

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The practice of exercise has shown to be beneficial to quality of life of individuals with HIV/AIDS. Thus, the present study analysed the effects of a combined exercise training in persons living with HIV/AIDS. Ten participants participated in the present study.

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Background: The aim of the present study was to evaluate the acute effects of resistance exercise (RE) leading to failure and RE that was not to failure on 24 h blood pressure (BP) and heart rate variability (HRV) in sedentary normotensive adult women.

Methods: Ten women (33.2 ± 5.

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Although aging compromises the functionality of macrophages (MΦ) and lymphocytes (LY), and dietary restriction (DR) and exercise partially counterbalance immunosenescence, it is unknown what effects of both strategies have on the functionality of these immune cells. Rats were randomly distributed into adult control (AD), older group (OLD), older submitted to 50% of DR (DR) and older submitted to swimming (EX) (n = 10 in each group). The function of immune cells (proliferative index, phagocytic capacity and H₂O₂ production), the weight and protein content of lymphoid organs (thymus and spleen), plasma glutamine concentration, interleukins (IL-1, IL-2, IL-6) and, immunoglobulins (IgA and IgG) were analysed.

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Purpose: To compare the metabolic parameters, flexibility, muscle strength, functional capacity, and lower limb muscle power of elderly women with and without the metabolic syndrome (MetS).

Methods: This cross-sectional study included 28 older women divided into two groups: with the MetS (n = 14; 67.3 ± 5.

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