Publications by authors named "James W Powell"

Article Synopsis
  • - Rabies is a serious disease that needs quick and accurate diagnosis to prevent its spread, with the direct fluorescent antibody (DFA) test currently being the standard method for post-mortem diagnosis.
  • - The LN34 pan-lyssavirus real-time RT-PCR assay shows great promise for diagnosing rabies, offering high sensitivity and the ability to work with various tissue types, even those that are deteriorated.
  • - In a study involving nearly 3,000 samples across several regions, the LN34 assay proved to be highly reliable, outperforming the DFA test in certain cases, revealing its potential for enhancing rabies diagnostics and surveillance efforts.
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White spot syndrome virus (WSSV) is a virulent pathogen of cultured shrimp and was first detected in farms in South Carolina (USA) in 1997 and subsequently in wild shrimp in 1999. We screened groups of 1808 wild Atlantic white shrimp Litopenaeus setiferus and 300 blue crabs Callinectes sapidus collected from South Carolina, Georgia, and Florida for the presence of WSSV using the Shrimple® immunoassay-strip test, with all positives and random subsets of negatives tested by TaqMan real-time PCR and in infectivity bioassays. Of 87 shrimp and 11 crabs that tested positive using the Shrimple® test, only a single C.

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Necropsy of an Atlantic bottlenose dolphin (Tursiops truncatus) neonate that stranded dead on Folly Beach, Charleston County, South Carolina, USA, on 17 November 2007, revealed multiple congenital heart malformations. Cardiac anomalies included a hypertrophic right ventricle, ventricular septal defect (VSD), aortic dilation, atrial septal defect (ASD) between a functionally common atrium and a left atrial remnant, subvalvular pulmonic stenosis, and a hypoplastic pulmonary artery and mitral valve. Few incidences of abnormal cardiac development in cetaceans have been published.

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We document the second known case of Cache Valley virus disease in a human. Cache Valley virus disease is rarely diagnosed in North America, in part because laboratories rarely test for it. Its true incidence, effect on public health, and full clinical spectrum remain to be determined.

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