Publications by authors named "James Tysome"

Background And Objectives: Surveillance studies offer sparse knowledge of predictors of future growth in sporadic vestibular schwannomas (VS).Our aim was identification of these risk factors. We propose a scoring system to estimate the risk of growth in sporadic vestibular schwannoma.

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Purpose: Retraction is the removal of published material due to flaws in research that cannot be corrected. Our aim was to perform a systematic review of all retracted literature in Ear Nose and Throat to understand the characteristics of retraction and the citations of retracted literature.

Methods: The Retraction Watch, EMBASE and MEDLINE databases were systematically searched to yield relevant retractions.

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Objectives: This systematic review and meta-analysis aimed to estimate the rate of taste disturbance following cochlear implantation.

Methods: The review was designed according to Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines. Included studies psychophysically measured taste.

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Objective: To investigate the clinical outcomes of bone-anchored hearing implant surgery using the MONO procedure.

Study Design: Multicenter, multinational, single-arm, prospective trial with a 12-month follow-up.

Setting: Seven European university hospitals from the United Kingdom, Sweden, Denmark, and The Netherlands.

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This research aims to enhance the understanding of the acoustic processes occurring during sonotubometry, a method used to assess the Eustachian tube (ET) function. Recent advancements in digital signal processing enable a more comprehensive data analysis. In this project, a silicone model of the ET was developed to systematically study the existing noise and sound sources.

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Idiopathic sudden sensorineural hearing loss (ISSNHL) is the rapid onset of reduced hearing due to loss of function of the inner ear or hearing nerve of unknown aetiology. Evidence supports improved hearing recovery with early steroid treatment, via oral, intravenous, intratympanic or a combination of routes. The STARFISH trial aims to identify the most clinically and cost-effective route of administration of steroids as first-line treatment for ISSNHL.

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Article Synopsis
  • * Participants used one of four hearing apps in controlled conditions and then three times at home, revealing strong correlations with PTA results for two of the apps.
  • * Most participants found the apps easy to use, and a significant percentage expressed a willingness to use them for ongoing hearing monitoring, suggesting that smartphone audiometry can be a viable remote assessment tool.
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 An operative workflow systematically compartmentalizes operations into hierarchal components of phases, steps, instrument, technique errors, and event errors. Operative workflow provides a foundation for education, training, and understanding of surgical variation. In this Part 1, we present a codified operative workflow for the retrosigmoid approach to vestibular schwannoma resection.

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 An operative workflow systematically compartmentalizes operations into hierarchal components of phases, steps, instrument, technique errors, and event errors. Operative workflow provides a foundation for education, training, and understanding of surgical variation. In this Part 2, we present a codified operative workflow for the translabyrinthine approach to vestibular schwannoma resection.

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Article Synopsis
  • The study aimed to determine the rate of postoperative meningitis following cochlear implantation in patients with inner ear malformations (IEMs) using meta-analysis.
  • A total of 38 studies were analyzed, revealing 10 cases of meningitis among 1300 malformed ears, resulting in an overall rate of 0.12%.
  • The research found that the risk of developing meningitis post-surgery in patients with IEMs is very low, especially noting that most cases were linked to intraoperative cerebrospinal fluid leaks.
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Objectives: To estimate the prevalence of, and risk factors associated with electrode migration (EM) in cochlear implant (CI) recipients.

Design: Historical cohort study of all CIs performed between 1 January 2018 and 1 August 2021 in a single tertiary adult and paediatric CI centre in the UK.

Main Outcome Measures: The primary aim is to determine the prevalence of electrode migration, comparing intraoperative surgeon report and examination of a routine plain radiograph performed 2 weeks after surgery.

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Article Synopsis
  • This study assesses the rate of postoperative meningitis in patients who receive cochlear implants (CIs) through a systematic review and meta-analysis of existing literature.
  • A total of 116 studies were included, revealing that out of 58,940 patients, there were 112 cases of meningitis, resulting in an estimated incidence rate of 0.07%.
  • The findings suggest that meningitis is a rare complication following CIs, with lower rates than earlier studies, especially in patients who received preventive measures like vaccinations and antibiotics.
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Objective: To investigate the value of scalp surface potentials to identify and manage partial short circuits to ground in cochlear implant electrodes.

Design: A retrospective review of patients with suspected partial short circuits.

Main Outcome Measure: Electrical output of individual electrodes was measured using scalp surface potentials for patients reporting a change in hearing function.

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Objective: To analyse the 2 and 5-year outcomes of a cohort of patients with newly diagnosed vestibular schwannoma patients.

Study Design: Longitudinal cohort study.

Setting: Tertiary skull base referral unit.

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Purpose: Primary: To determine the rate of occult cervical metastases in primary temporal bone squamous cell carcinomas (TBSSC). Secondary: to perform a subgroup meta-analysis of the risk of occult metastases based on the clinical stage of the tumour and its risk based on corresponding levels of the neck.

Methods: A systematic review and meta-analysis of papers searched through Medline, Cochrane, Embase, Scopus and Web of Science up to November 2021 to determine the pooled rate of occult lymph node/parotid metastases.

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Objectives: Nurses are increasingly providing routine and emergency ENT care; yet there are often limited training opportunities. The aim of this study was to validate an intensive 1-day ENT emergency simulation course for nurses.

Methods: The course included short lectures, practical skills stations and mannequin simulation scenarios.

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Objective: To review the outcomes of cochlear implants (CI) in patients with neurofibromatosis type 2 (NF2) in a large cohort, and identify factors associated with poor hearing benefit.

Study Design: Fifteen-year retrospective national observational case series.

Setting: United Kingdom regional NF2 multidisciplinary teams.

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Objective: The growth characteristics of vestibular schwannomas (VSs) under surveillance can be studied using a Bayesian method of growth risk stratification by time after surveillance onset, allowing dynamic evaluations of growth risks. There is no consensus on the optimum surveillance strategy in terms of frequency and duration, particularly for long-term growth risks. In this study, the long-term conditional probability of new VS growth was reported for patients after 5 years of demonstrated nongrowth.

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Objectives: To investigate the combined effect of changing pulse shape and grounding configuration to manage facial nerve stimulation (FNS) in cochlear implant (CI) recipients.

Patients: Three adult CI recipients with severe FNS were offered a replacement implant when standard stimulation strategies and programming adjustments did not resolve symptoms. Our hypothesis was that the facial nerve was less likely to be activated when using anodic pulses with "mixed-mode" intra-cochlear and extra-cochlear current return.

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Introduction: Depending on severity of presentation, pituitary apoplexy can be managed with acute surgery or non-operatively. We aim to assess long-term tumour control, visual and endocrinological outcomes following pituitary apoplexy with special emphasis on patients treated non-operatively.

Methods: Multicentre retrospective cohort study.

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Objective: To determine outcomes following cochlear implantation (CI) in children with autism spectrum disorder (ASD).

Databases Reviewed: MEDLINE, Embase, Web of science, Cochrane Library, and Clinicaltrial.gov.

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Introduction: The prevalence of hearing loss and its consequences is increasing as the elderly population grows. As the guidelines for cochlear implantation (CI) expand, the number of elderly CI recipients is also increasing. We report complication rates, survival duration, and audiological outcomes for CI recipients aged 80 years and over and discuss the cost utility of CI in this age group.

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