Relationship Between EEG Electrode and Functional Cortex in the International 10 to 20 System.

Introduction: In this study, we attempted to define the variability in the anatomical relationship between scalp EEG electrodes and eloquent cortical function, as inferred from fMRI.

Methods: MRI-compatible fiducial markers were positioned at locations of CZ, C3 and C4, T3 and T4, and F7 and F8 in 10 healthy subjects. Well-validated fMRI paradigms were administered to activate primary motor cortex and language regions, and the distance between these brain regions and fiducial markers was measured.

Quality of life one year after epilepsy surgery.

Background: The aim of surgery for medically intractable epilepsy was to achieve seizure freedom and improve overall quality of life (QOL) in patients. This investigation looked at changes in QOL one year after epilepsy surgery and the relationship of changes to mood, language, and seizure outcomes.

Method: Depressive symptoms, QOL, and naming were measured in 25 patients with temporal lobe epilepsy before and one year after dominant temporal lobe resection.

Left or right? Lateralizing temporal lobe epilepsy by dynamic amygdala fMRI.

Objectives: In this case series, the findings of 85 functional MRI studies employing a dynamic fearful face paradigm are reported. Previous findings have shown the paradigm to generate bilateral amygdala activations in healthy subjects and unilateral activations in patients with MTLE, in the contralateral hemisphere to seizure origin. Such findings suggest ipsilateral limbic pathology and offer collateral evidence in lateralizing MTLE.