Publications by authors named "James T Parker"

Article Synopsis
  • Systemic lupus erythematosus (SLE) is a chronic autoimmune disease that can affect multiple organs, with kidney issues (lupus nephritis) being a serious complication and a leading cause of death in affected patients.
  • Current mouse models used to study SLE/LN show diverse immune responses that may not fully reflect human disease, highlighting the need for better models that parallel human pathways for developing new treatments.
  • The research compared the immune responses of five different mouse models of SLE/LN to human data, finding differences in cell types and responses, which could help in understanding the disease and improving therapy translation for patients.
View Article and Find Full Text PDF

Purpose: School-based sexual health education (SHE) can teach students critical knowledge and skills. For effective SHE, school districts can offer support, including strong curricula and professional development. This study assessed changes in students' sexual health knowledge and sexual behaviors following implementation of enhanced support for SHE delivery in one school district.

View Article and Find Full Text PDF

Objectives: To evaluate the introduction of pharmacist independent prescribing activity across three general critical care units within a single large UK teaching hospital. To identify the prescribing demographics including total of all prescriptions, number prescribed by pharmacists, reason for pharmacist prescription, range of medications prescribed, pharmacist prescribing error rate and the extent of pharmacist second 'clinical check'.

Methods: Retrospective evaluation of e-prescribing across all general critical care units of a single large UK teaching hospital.

View Article and Find Full Text PDF

Recent studies have mapped the keto-enol tautomerization of malonaldehyde through a general transition structure that leads exclusively to the Z isomer of the enol. However, it will be shown that a competing general transition structure exists that leads to both the E and Z isomers of the enol at the B3LYP/6-31G(d,p) and MP2/6-31G(d,p) levels of theory. Both the RHF- and DFT-based effective fragment potential methods have been used to model solvation effects, and the results are compared with full ab initio calculations.

View Article and Find Full Text PDF

In two experiments, we examined training, retention, and transfer of a duration production skill in a prospective paradigm. Participants were trained with feedback and then were either tested immediately for transfer without feedback or retrained with feedback 1 week later. There were three training and retraining conditions, two involving secondary tasks.

View Article and Find Full Text PDF

We conducted two experiments to study the training of speeded responses to stimuli in a clock face array. Participants were trained on one clock face and later tested on either the same or a different clock face. The clock faces varied along 3 dimensions of change (left-right flip, up-down flip, and 180 degrees rotation).

View Article and Find Full Text PDF

Adults recalled the order of the letters in one of two four-letter segments following a distractor task. They knew in advance the identity of the letters in each segment. A letter was made distinctive by replacing it with a red dash.

View Article and Find Full Text PDF