Publications by authors named "James Sweeney"

Accurate and efficient valuation of property is of utmost importance in a variety of settings, such as when securing mortgage finance to purchase a property, or where residential property taxes are set as a percentage of a property's resale value. Internationally, resale based property taxes are most common due to ease of implementation and the difficulty of establishing site values. In an Irish context, property valuations are currently based on comparison to recently sold neighbouring properties, however, this approach is limited by low property turnover.

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In Ireland, the interferon-gamma (IFN-γ) assay is routinely used as an ancillary test interpreted in parallel with the single intradermal comparative tuberculin test (SICTT) to maximize the detection of bovine tuberculosis (bTB) infected animals. Up until 2018, a positive test result was recorded in the IFN-γ ELISA assay following whole blood stimulation with purified protein derivative (PPD)-bovine (B), PPD-avian (A) and nil sample (N), using the interpretation criteria, B-N > 50 optical density units (OD), B > 100 and B-A > 0. Following a review of available data, the threshold of the B-A component changed to B-A > 80.

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We propose to embed time series in a latent space where pairwise Euclidean distances (EDs) between samples are equal to pairwise dissimilarities in the original space, for a given dissimilarity measure. To this end, we use auto-encoder (AE) and encoder-only neural networks to learn elastic dissimilarity measures, e.g.

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Right ventricular (RV) dysfunction and resultant acute right heart failure (ARHF) is a rapidly growing field of interest, driven by increasing appreciation of its contribution to heart failure morbidity and mortality. Understanding of ARHF pathophysiology has advanced dramatically over recent years and can be broadly described as RV dysfunction related to acute changes in RV afterload, contractility, preload, or left ventricular dysfunction. There are several diagnostic clinical signs and symptoms as well as imaging and hemodynamic assessments that can provide insight into the degree of RV dysfunction.

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A prototype main-ion CHarge Exchange Recombination Spectroscopy (mCHERS) diagnostic is providing measurements of the main-ion (hydrogen or deuterium) temperature and velocity in the C-2W field reversed configuration plasma using charge exchange Balmer-alpha emission at five different radial locations with 500 Hz frequency and a per-pixel velocity resolution of 15 km/s. Measurement along the entire plasma radius of C-2W is enabled by a diagnostic neutral beam (DNB) that passes through the center of plasma, unlike the larger diameter heating neutral beams that have impact parameters of 20 cm. DNB provides high time resolution via beam modulation and spatial resolution via its small cross section.

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Dynamic loading is a shared feature of tendon tissue homeostasis and pathology. Tendon cells have the inherent ability to sense mechanical loads that initiate molecular-level mechanotransduction pathways. While mature tendons require physiological mechanical loading in order to maintain and fine tune their extracellular matrix architecture, pathological loading initiates an inflammatory-mediated tissue repair pathway that may ultimately result in extracellular matrix dysregulation and tendon degeneration.

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Strategies adopted globally to mitigate the threat of COVID-19 have primarily involved lockdown measures with substantial economic and social costs with varying degrees of success. Morbidity patterns of COVID-19 variants have a strong association with age, while restrictive lockdown measures have association with negative mental health outcomes in some age groups. Reduced economic prospects may also afflict some age cohorts more than others.

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Introduction: Bovine tuberculosis (bTB) is an important zoonotic disease which has serious and sometimes fatal effects on both human and non-human animals. In many countries it is endemic in the cattle population and has a considerable economic impact through losses in productivity and impacts on trade. The incidence rate in Ireland varies by herd and location and it is hoped that statistical disease-mapping models accounting for both spatio-temporal correlation and covariates might contribute towards explaining this variation.

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A main ion charge exchange recombination spectroscopy (mChERS) diagnostic has been developed to measure the velocity and temperature of the main deuterium ions in the C-2W (also called Norman) field-reversed configuration (FRC) device. A modulated diagnostic neutral beam (DNB) of hydrogen with 40 keV full energy and a nominal current of 8.5 A provides the charge exchange signal.

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Background: Textbook depictions of the mitral valve (MV) often illustrate it as composed of a single nonscalloped anterior leaflet, with the posterior leaflet having three symmetric and evenly spaced scallops. However, common variations in this anatomy have been noted in autopsy series for decades. Improved cardiac imaging with three-dimensional transesophageal echocardiography (TEE) now affords the ability to detect variations in scallop anatomy in vivo.

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Lyme disease (LD) is the most common tick-borne illness in Europe. Population-based studies in European children are few. This study aimed to assess the incidence, clinical presentation, treatment and outcome of serologically confirmed paediatric LD in the Republic of Ireland over a 5-year period.

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Background: The failure of some high-income countries to retain their medical graduates is one driver of doctor immigration from low- and middle-income countries. Ireland, which attracts many international medical graduates, implemented a doctor retention strategy from early 2015. This study measures junior doctors' migration intentions, the reasons they leave and likelihood of them returning.

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Although inspiratory muscle training (IMT) is reported to improve inspiratory muscle strength in humans little has been reported for horses. We tested the hypothesis that IMT would maintain and/or improve inspiratory muscle strength variables measured in Thoroughbreds during detraining. Thoroughbreds from one training yard were placed into a control (Con, n = 3 males n = 7 females; median age 2.

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Several studies of neurocognitive differences between selected samples of nonimpact and impact patients experiencing mild traumatic brain injury (mTBI) in a single motor vehicle accident have been conducted. The results suggested comparable and essentially normal brain-related cognitive skills for these clinical groups, but with notable exceptions for nonimpact individuals involving tactile- and visual-spatial perceptual and memory deficiencies. These findings raised the possibility that some nonimpact patients were experiencing dysfunction of post-central cerebral regions due to neck injury that was interfering with vertebral artery function.

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Background: Routine clinical outcome monitoring (RCOM) is the standardised gathering of measures of clinical outcomes in everyday practice. HoNOS (Health of the Nation Outcome Scales) is a tool used in RCOM.

Aims: To examine (a) agreement between HoNOS and Global Assessment of Functioning (GAF), (b) HoNOS changes over time/attendance and (c) clinical parameters affecting HoNOS scores.

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Sweeney and Johnson found that response time on the Tactile Form Recognition Test (TFR) of the Halstead-Reitan Test Battery (HRB) requiring speeded tactile- and visual-spatial recognition was deficient for Nonimpact mild traumatic brain injury (mTBI) individuals in comparison to Impact mTBI and No mTBI participants. A follow-up study by Sweeney and Slade noted that skills most sensitive to Deficient TFR performance of mTBI subjects involved tactile-spatial perception, with lateralization of inferior performances contralateral to cerebral regions known to specialize in the spatial skills required. The current study compared frequencies of HRB Pathognomonic Signs, atypical Score Patterns, and abnormal Right-Left Differences for Nonimpact mTBI groups that exhibited Deficient, Perfectly Normal, or Normal TFR performances.

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Sweeney and Johnson found that individuals that sustained mild traumatic brain injury without impact to the head (Nonimpact) demonstrated significantly slower performance than participants that suffered mild traumatic brain injury with impact to the head and normal controls on the Tactile Form Recognition Test (TFR). The current study explored the spatial cognition of three groups of Nonimpact participants classified as Deficient, Perfectly Normal, and Normal on the basis of TFR response time. Dependent variables consisted of neuropsychological tests requiring tactile- and/or visual-spatial perception and memory.

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This study investigated the degree to which litigants/insurance claimants sustaining Nonimpact mild traumatic brain injury (mTBI) in motor vehicle accidents differed from compensation-seeking motor vehicle accident victims that suffered Impact mTBI in terms of neuropsychological decline/recovery, using as a control litigants/insurance claimants that did not experience mTBI in motor vehicle accidents. A clinical index (C-Voc) was employed as the dependent measure for decline/recovery, consisting of T-score algebraic differences between a highly sensitive neurocognitive measure (Category Test) and a relatively insensitive "hold" measure (Wechsler Adult Intelligence Scale Vocabulary subtest). Nonimpact mTBI subjects showed significantly greater neurocognitive decline than Impact mTBI participants and, interestingly, Impact mTBI individuals did not differ significantly from individuals with no diagnosis of mTBI.

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The purpose of this study was to investigate possible neuropsychological differences in Halstead-Reitan characteristics between motor vehicle accident litigants and insurance claimants that sustained uncomplicated mild traumatic brain injury (mTBI) and did or did not sustain direct impact to the head (i.e., Impact vs.

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A number of analyses, meta-analyses, and assessments, including those performed by the Intergovernmental Panel on Climate Change, the National Oceanic and Atmospheric Administration, the National Renewable Energy Laboratory, and the International Energy Agency, have concluded that deployment of a diverse portfolio of clean energy technologies makes a transition to a low-carbon-emission energy system both more feasible and less costly than other pathways. In contrast, Jacobson et al. [Jacobson MZ, Delucchi MA, Cameron MA, Frew BA (2015) Proc Natl Acad Sci USA 112(49):15060-15065] argue that it is feasible to provide "low-cost solutions to the grid reliability problem with 100% penetration of WWS [wind, water and solar power] across all energy sectors in the continental United States between 2050 and 2055", with only electricity and hydrogen as energy carriers.

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Patients subjected to severe acceleration forces in motor vehicle accidents that met criteria for uncomplicated mild traumatic brain injury (mTBI) in the absence of direct impact to the head were examined neuropsychologically using the Halstead-Reitan Neuropsychological Test Battery. The subjects were litigants and/or insurance claimants for whom there was psychometric evidence of acceptable test effort. The purpose of the study was to provide descriptive neuropsychological data for this particular clinical population.

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Comparisons were made between neuropsychological deficit scores generated by the Reitan-Wolfson system of interpretation (1993) and the computerized Revised Comprehensive Norms for an Expanded Halstead-Reitan Battery (Heaton, Miller, Taylor, Grant, & PAR Staff, 2005 ). The scores were obtained from seat-belted litigants and insurance claimants subjected to extreme physical forces in motor vehicle accidents. Subjects had not sustained direct impact to the head but met criteria for mild traumatic brain injury.

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