Recurrent status epilepticus as the primary neurological manifestation of CADASIL: A case report.

Cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL) often presents with a history of migraine with aura and eventual manifestations of dementia with unrelenting, repeated cerebral vascular insults. Only 6-10% of patients with CADASIL have been reported to develop seizures, and status epilepticus (SE) is exceedingly rare. Here, we describe a patient who presented with recurrent SE, with eventual biopsy diagnosis of CADASIL.

Spinal epidural hematoma: an important stroke mimic.

Tissue plasminogen activator (tPA) is, on occasion, given to patients who do not suffer from acute cerebral ischemia. As the underlying conditions often mistaken for acute ischemic stroke tend to produce transient dysfunction, and are generally seen in individuals younger than stroke patients, the outcome of such mistaken treatment is generally benign. We will describe two elderly patients with acute hemiparesis caused by spinal epidural hematomas (SEDH), both of whom were initially considered candidates for tPA.

Effects of Mendelsohn maneuver on measures of swallowing duration post stroke.

Purpose: The purpose of this pilot study was to determine whether intensive use of the Mendelsohn maneuver in patients post stroke could alter swallow physiology when used as a rehabilitative exercise.

Method: Eighteen outpatients between 6 weeks and 22 months post stroke were enrolled in this prospective study using a crossover design to compare 2 weeks of treatment with 2 weeks of no treatment. Each participant received an initial videofluoroscopic swallow study (VFSS) and an additional VFSS at the end of each week for 1 month for a total of 5 studies.

Cerebral infarcts in the setting of eosinophilia: three cases and a discussion.

Objective: To describe 3 cases of stroke associated with hypereosinophilic syndrome and discuss the pathogenesis of such strokes.

Design: Retrospective medical record review.

Setting: University hospital.

An unusual case of multiple discrete brain lesions.

The case of a patient with multiple enhancing lesions in the brain is presented, along with discussion of the differential diagnosis of granulomatous lesions of the brain, and a brief review of the essential features and neurological complications of the eventual diagnosis. Aspects of the disease of interest to neurologists are emphasized.

Motor neuron disease presenting with slow saccades and dementia.

A 46-year-old man with a 2-year history of dementia presented with very slow saccades and tongue fasciculations. The diagnosis of amyotrophic lateral sclerosis (ALS) was established by electrophysiologic studies and ultimately on autopsy. Rarely, slowed saccades may be present in ALS, and slow saccades in a relatively young demented patient should prompt consideration of ALS.