GUIDELINE-DIRECTED MEDICAL THERAPY FOR HEART FAILURE: REAL-WORLD EVIDENCE IN ONE LATIN-AMERICAN CENTER.

Background: Despite recommendations from clinical practice guidelines to initiate four drug classes in patients with heart failure (HF) with reduced ejection fraction, information on real-world implementation remains limited. This study evaluated the medications initiated and titrated, the time until the optimal treatment tolerated, pharmacological profiles, patient's adherence, and causes of non-use of guideline directed-medical therapy (GDMT) in a cohort of patients with HF.

Methods: A retrospective cohort study was conducted on patients treated in a heart failure program in Colombia.

Chest pain and acute coronary syndrome in octogenarians admitted to the Emergency Department.

Background: Although chest pain and acute coronary syndrome (ACS) are among the most common complaints in the Emergency Departments (ED), little is known about this topic in the octogenarian population.

Objectives: This study aimed to describe the clinical presentation and to evaluate survival time according to the ACS type in a group of 80-year-old or over patients admitted for chest pain to an ED.

Methods: Patients were classified according to the discharge diagnosis.