3D Magnetic Particle Imaging of Human Stem Cell-Derived Islet Organoid Transplantation Using a Machine Learning Algorithm.

Stem cell-derived islet organoids constitute a promising treatment of type 1 diabetes. A major hurdle in the field is the lack of appropriate method to determine graft outcome. Here, we investigate the feasibility of tracking of transplanted stem cell-derived islet organoids using magnetic particle imaging (MPI) in a mouse model.