Synopsis of recent research by authors named "James Pilling"
James Pilling's recent research primarily focuses on understanding the mechanisms of cancer resistance and relapse, particularly involving secreted proteins and the role of the Hippo pathway in lung cancer, using innovative techniques such as CRISPR screening and image-based profiling.
His findings highlight the significance of tumor dormancy in breast cancer and the challenges it poses for treatment, while also unveiling crucial resistance genes related to EGFR mutant lung cancer.
Additionally, Pilling's work explores the therapeutic potential of nanoparticle formulations for enhancing drug delivery and effectiveness in treating various cancers, including lymphoma and acute myeloid leukemia, underscoring the importance of optimizing treatment modalities.