Publications by authors named "James O Noxon"

Article Synopsis
  • - The study investigates the effectiveness of next-generation sequencing (NGS) versus traditional culture methods in identifying bacteria and testing antibiotic resistance in dogs with superficial bacterial folliculitis (SBF), primarily caused by Staphylococcus pseudintermedius.
  • - Twenty-four dogs with SBF were sampled using sterile swabs, and the results showed that NGS identified more bacterial organisms than culture methods, but there was no significant difference in turnaround time.
  • - Ultimately, the research concludes that NGS is not a suitable replacement for traditional culture methods in diagnosing and treating SBF in dogs at this time due to inconsistencies in resistance detection.
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Background: Treatments currently available for ceruminous gland tumors include surgery and radiation therapy, which come with high financial costs and frequent complication and recurrence rates.

Hypothesis: To evaluate the treatment, response, complication, and recurrence of ceruminous gland tumors confirmed with biopsy and ablated using CO laser.

Methods: Retrospective review of medical records from Iowa State University and the University of Illinois between January 1, 2016 and December 31, 2021.

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Background: There are limited clinical studies evaluating the Trichophyton mentagrophytes complex, with most reports confined to small case studies. Additionally, the studies are dated and provide limited information on response to newer or currently available therapies.

Hypothesis/objectives: The aim of the study was to determine if there is a breed prevalence, lesion distribution and seasonality associated with the T.

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Background: Ceftazidime (CAZ) solutions are being used based on anecdotal reports for otitis externa complicated by multidrug-resistant Pseudomonas aeruginosa (MDR PA). The chemical and microbiological stability of these proposed compounded solutions have not been evaluated, and likely are affected by the diluent and storage duration or temperature.

Hypothesis/objectives: Compounded CAZ solutions would show variable degradation dependent on diluent, time and temperature.

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Background: The aetiology and appropriate treatment for auricular chondritis in the dog are currently unclear. This report describes a unique presentation and successful treatment of a dog with auricular chondritis.

Clinical Summary: A 12-year-old, female spayed, Labrador retriever dog was presented for severe pain thought to be neurological in origin.

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The use of human generic amoxicillin-clavulanic acid formulations in veterinary medicine is currently lacking supportive evidence. This pilot study was conducted to determine preliminary pharmacokinetic parameters and relative oral bioavailability of a human generic and veterinary proprietary 4:1 amoxicillin-clavulanic acid formulation in healthy dogs to evaluate whether drug exposure was similar and to determine if further comparative investigation is warranted. Each dog received a single oral dose of each formulation containing 500:125 mg of amoxicillin-clavulanic acid at two separate instances with a 2 wk washout period between product administration.

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In veterinary medicine, Staphylococcus schleiferi was previously assumed to be an inhabitant of carnivore skin, however, more recently, it has been repeatedly documented in the literature as both an inhabitant and as a pathogen. In order to determine the frequency of nasal carriage, and the methicillin susceptibility pattern of S. schleiferi from healthy dogs as well as dogs with otitis and/or pyoderma, a prospective study including 24 dogs with healthy ears and skin, 27 dogs with healthy ears and pyoderma, 15 dogs with otitis without pyoderma and 20 dogs with both otitis and pyoderma was performed.

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Terbinafine is an allylamine antifungal prescribed for the treatment of mycoses in humans. It is increasingly being used in veterinary patients. The purpose of this study was to evaluate the pharmacokinetic properties of terbinafine in dogs after a single oral dose.

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A shortage of veterinary educators in various clinical disciplines is requiring faculty at veterinary schools to develop novel approaches to teaching professional students a core of information in each major clinical discipline. This article presents experiences at Washington State University (WSU) College of Veterinary Medicine in the teaching of the didactic components of ophthalmology and dermatology over four years using pre-prepared lectures developed by off-site instructors. The methodology of lecture preparation and presentation and various perspectives of student satisfaction with this teaching/learning method are presented.

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