Publications by authors named "James M Pattison"
Article Synopsis
- Nephropathy caused by the BK virus (BKVAN) is a significant issue leading to kidney transplant failure, prompting a study on the effectiveness of lab markers for monitoring patients post-diagnosis.
- Serial urine and serum samples from seven patients with confirmed BKVAN showed a decrease in viral load and associated markers following treatment modifications, such as reduced immunosuppression and antiviral therapy.
- Findings suggest that negative electron microscopy and the absence of decoy cells are good indicators of treatment response, while BK virus DNA levels offer a more precise assessment of viral control.
We describe the case of a 22-year-old Portuguese renal transplant patient whose post-transplant course was complicated by prolonged delayed graft function and pyrexia of unknown origin. Conventional imaging techniques were not definitive, but positron-emission tomography (PET) scanning identified abnormalities in the lung and mediastinum that led to a diagnostic biopsy demonstrating mycobacterial infection.
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