Dexmedetomidine for Sedation During Noninvasive Ventilation in Pediatric Patients.

Objectives: To describe the use of dexmedetomidine for sedation in a large cohort of nonintubated children with acute respiratory insufficiency receiving noninvasive ventilatory support.

Design: Single-center, retrospective, observational cohort study.

Setting: A large quaternary-care PICU.

Remifentanil for Sedation of Children With Traumatic Brain Injury.

Objective: To determine whether remifentanil would provide adequate sedation while allowing frequent and reproducible neurologic assessments in children admitted to the pediatric intensive care unit (PICU) with traumatic brain injury (TBI) during mechanical ventilation.

Design: Retrospective review.

Setting: Tertiary care PICU.