Publications by authors named "James Krause"

Article Synopsis
  • - The study aimed to investigate prescription benzodiazepine use among adults with chronic spinal cord injury (SCI), focusing on frequency, concurrent opioid use, and related sociodemographic factors.
  • - Out of 918 participants, 20% reported any benzodiazepine use in the past year, with 13% using it weekly; 6.5% reported using both benzodiazepines and opioids concurrently.
  • - The results indicated older adults and non-Hispanic Blacks were less likely to use benzodiazepines, while those using opioids weekly had significantly higher odds of benzodiazepine use, highlighting potential risks associated with concurrent medication use.
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Background: There is limited understanding of the relationships between prescription opioid and benzodiazepine use and indices of health-related quality of life (HRQOL) among those with spinal cord injuries (SCI).

Objective: To identify the relationships between self-reported prescription opioid and benzodiazepine use and two indicators of HRQOL, number of days in poor physical health and poor mental health in the past 30 days among adults with SCI.

Methods: A cross-sectional cohort study of 918 adults with chronic (>1 year), traumatic SCI living in the Southeastern United States was conducted.

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Context: Having dependable attendant care is essential to the health and well-being of those most severely impacted by a spinal cord injury (SCI). Our objective was to identify how often people with SCI who require assistance for transfers either spend a full day in bed or all night in a wheelchair because they do not have paid or unpaid assistance.

Findings: Of the 918 respondents, 319 (34.

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Objective: To identify the relations of 3 frequently used prescription opioids (hydrocodone, oxycodone, tramadol) with unintentional injuries, including fall-related and non-fall-related injuries among adults with chronic, traumatic spinal cord injury (SCI).

Design: Cross-sectional cohort study.

Setting: Community setting; Southeastern United States.

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Objective: To identify changes in health, health care utilization, participation, life satisfaction, and depressive symptoms from before the coronavirus disease 2019 pandemic to after among ambulatory and nonambulatory participants with spinal cord injury.

Design: Longitudinal study with the first measurement taken within 3 months prior to pandemic restrictions and 2 follow-ups at approximately 1-year intervals.

Setting: Medical university.

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Objectives: To examine the relations of pain intensity, opioid use, and opioid misuse with depressive symptom severity and probable major depression (PMD) among participants with spinal cord injuries (SCI), controlling for demographic, injury, and socioeconomic characteristics.

Study Design: Cohort study.

Setting: Medical University in the Southeastern United States (US).

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Objective: To develop longitudinal structural models of social isolation and probable major depression (PMD) over a 5-year interval among participants with spinal cord injury (SCI).

Design: Longitudinal structural equation modeling of self-report assessments collected during two follow-ups (2013 as Time 1, 2018 as Time 2) of a 45-year multicohort longitudinal study. Participants ( = 557) were identified from a specialty hospital in the Southeastern United States and two Midwestern hospitals and were initially enrolled in 1973-1974, 1984-1985, 1993-1994, or 2003-2004.

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Background: Individuals with spinal cord injuries (SCI) experience high rates of prescription opioid use, yet there is limited data on frequency of opioid use and specific medications being taken.

Objectives: To examine the frequency of self-reported prescription opioid use among participants with SCI and the relationship with demographic, injury, and socioeconomic characteristics.

Methods: A cohort study of 918 adults with SCI of at least 1-year duration completed a self-report assessment (SRA) that indicated frequency of specific prescription opioid use based on the National Survey on Drug Use and Health (NSDUH).

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Purpose: People with spinal cord injury (PwSCI) can experience life changes, including impacts on their physical and mental health. PwSCI often report less life satisfaction and lower subjective well-being than peers without SCI. These challenges and adversities increase the demand on them to be more resilient.

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Objective: To examine change in pain interference and depression over a 10-year time period in individuals with long-term traumatic spinal cord injury (SCI) and to identify the extent to which changes in pain interference over time predicts change in depressive symptoms.

Design: Longitudinal analyses of self-report assessment data.

Setting: Specialty and university hospitals in the Southeastern and Midwestern United States.

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To identify differences in personal characteristics, health outcomes, and hospital utilization as a function of ambulatory status among adults with chronic SCI. Prospective cohort study linked to state administrative billing data. Population-based SCI Registry from the Southeastern United States.

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Objective: To describe the self-reported difficulties during the COVID-19 pandemic on the lives of persons with traumatic spinal cord injury (SCI), and to identify the factors measured prior the pandemic that predict the number of difficulties obtaining daily necessities and difficulties obtaining SCI services during the pandemic.

Design: Cohort study.

Setting: A state SCI outcomes follow-up database in the southeastern United States.

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Purpose/objective: To evaluate the acceptability and feasibility of testing the cognitive abilities of adults with traumatic spinal cord injury (TSCI) via teleconference.

Research Design: Data were collected prospectively at two study sites from 75 adults living with TSCI. Participants completed a series of self-report measures via an online survey platform, in addition to a brief battery of cognitive testing administered via audio-video teleconference.

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Objective: To describe the self-reported impact of the COVID-19 pandemic on the lives of persons with spinal cord injury (SCI).

Design: Cross sectional study.

Participants: There were a total of 382 adult participants with traumatic SCI of at least one-year duration, all of whom were identified through a state-based surveillance registry in the Southeastern United States.

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Objective: To examine high-risk opioid prescription metrics among individuals with chronic spinal cord injury (SCI) living in South Carolina.

Design: Cohort Study.

Setting: Two statewide population-based databases, an SCI Surveillance Registry and state prescription drug monitoring program (PDMP).

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Study Design: Cohort study.

Objective: To identify five-year longitudinal changes in employment, health, participation, and quality-of-life outcomes (QOL) among participants with chronic spinal cord injury (SCI) and to compare the amount of change in these outcomes between those surviving and those not surviving until follow-up.

Methods: Participants were 1157 individuals from the SCI Longitudinal Aging Study, who have completed at least two self-report assessments separated by five-year intervals.

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Background: Individuals with traumatic spinal cord injuries (SCIs) have lower subjective well-being and diminished longevity, yet there is a lack of research on how life satisfaction and changes in life satisfaction relate to longevity.

Objectives: To identify the relationships between survival status and life satisfaction and its changing trend over a 10-year period.

Methods: Data were taken from the SCI Longitudinal Aging Study.

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Objective: To identify job characteristics related to perceived underemployment among people with spinal cord injury (SCI), while controlling for demographic, injury, and educational factors.

Design: Cross-sectional, logistic regression with predicted probabilities of underemployment

Setting: Medical University in the Southeastern United States.

Participants: 952 were adults with traumatic SCI, all of whom were a minimum of 1-year post-injury and employed at the time of the study.

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Objective: To identify how prediagnosis employment, education, demographic statuses, and disease factors relate to job retention among people with multiple sclerosis (MS).

Design: Cross-sectional logit model.

Setting: Data were collected at an academic Medical University and a specialty hospital, both in the Southeastern US.

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Objective: Identify the relationship of health conditions with self-reported emergency department (ED) visits and ED-related hospitalizations among people with traumatic spinal cord injury (SCI), while controlling for demographic, injury, and socioeconomic factors.

Design: Cross-sectional.

Setting: A regional SCI model system in the Southeastern United States.

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Study Design: Cohort study.

Objective: Previous research has indicated that socioeconomic factors affect longevity after traumatic spinal cord injury (SCI). Our purpose was to evaluate whether social participation mediates the relationship between socioeconomic factors and survival status after SCI.

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Study Design: Cross-sectional study.

Objective: To identify demographic, injury, and behavioral predictors of emergency department (ED) visits and ED-related hospitalizations among individuals with chronic traumatic spinal cord injury (SCI).

Setting: An academic medical center in the Southeastern United States.

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Objective: To investigate the association of behavioral factors with retrospective reports of staying free from pressure injuries (PIs) during a 12-month period for people with chronic spinal cord injury (SCI).

Design: Cross-sectional survey.

Setting: Data collection was completed at an academic medical center in the Southeastern United States in collaboration with a specialized treatment center and 2 public health registries that use population-based approaches to identify all incident cases of SCI within the state.

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Objective: Our objective was to identify the number, length of stay, and charges of rehospitalizations during the subsequent 5 years after discharge from the initial hospitalization by using administrative billing records from a population-based cohort with spinal cord injury (SCI) in the southeastern United States.

Design: Analysis of administrative billing data.

Setting: State-based surveillance data analyzed by an academic medical center in the southeastern United States.

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