Publications by authors named "James H"

Some research suggests that risk adjustment plays a substantial role in explaining the high levels of government spending on Medicare Advantage (MA). We studied whether the reliance on diagnosis codes to risk-adjust payments to MA plans leads to the inflation of submitted diagnoses. Our approach relied on a comparison among diagnoses included in hospital claims, health status measures from similarly timed health assessments completed by skilled nursing facility (SNF) clinicians, and short-term mortality data.

View Article and Find Full Text PDF

Osteological data, such as biological sex, constitute a base for research in paleodemography and palaeopathology, as well as for understanding past socio-cultural practices. Despite extensive research efforts concerning cremated human remains over the past decades, an internationally acknowledged, standardized osteological protocol is not fully agreed upon. Furthermore, assessing cremation research practices from the literature is challenging because analysis reports are often written in the national languages of practitioners, which makes them difficult to access by an international audience.

View Article and Find Full Text PDF
Article Synopsis
  • Many pregnant women are unsure about taking antidepressants because they worry about the risks and how it might affect their baby.
  • The study talked to 22 women who experienced depression during pregnancy, and half of them used antidepressants.
  • The women wanted more information to help them make better decisions about using medication while dealing with their struggles during pregnancy.
View Article and Find Full Text PDF

Background: Reusable surgical drapes have a lower lifetime environmental impact than disposable drapes in most cases. There is limited evidence regarding whether drape choice impacts patient outcomes including post-operative wound complications. The aim of this study is to compare wound complication rates following routine neutering surgeries in cats and dogs when reusable drapes are used as compared with disposable drapes.

View Article and Find Full Text PDF

This report details a hybrid approach for treatment of abdominal aortic aneurysm in a patient with Marfan syndrome (MFS). A 34-year-old patient with MFS and prior open thoracoabdominal aortic aneurysm repair underwent bilateral common iliac artery interposition graft repair and endovascular aortic repair. The bifurcated stent graft was implanted into the previous thoracoabdominal graft proximally and iliac interposition grafts distally.

View Article and Find Full Text PDF
Article Synopsis
  • Communication skills are essential in medicine, but postgraduate training often lacks proper instruction in serious illness communication skills (SICS), leaving residents feeling unprepared for difficult conversations.
  • An innovative e-module was developed to teach core SICS, allowing residents to practice through structured role-plays and receive feedback, which replaced traditional lectures.
  • The study found that residents preferred mixed learning methods, felt more prepared for advanced care planning discussions after the intervention, and showed a growing interest in these conversations, despite concerns about their practicality in busy clinical settings.
View Article and Find Full Text PDF

Biomolecular condensates play a major role in numerous cellular processes, including several that occur on the surface of lipid bilayer membranes. There is increasing evidence that cellular membrane trafficking phenomena, including the internalization of the plasma membrane through endocytosis, are mediated by multivalent protein-protein interactions that can lead to phase separation. We have recently found that proteins involved in the clathrin-independent endocytic pathway named Fast Endophilin Mediated Endocytosis can undergo liquid-liquid phase separation (LLPS) in solution and on lipid bilayer membranes.

View Article and Find Full Text PDF

Background: Photographs from medical case reports published in academic journals have previously been found in online image search results. This means that patient photographs circulate beyond the original journal website and can be freely accessed online. While this raises ethical and legal concerns, no systematic study has documented how often this occurs.

View Article and Find Full Text PDF

Introduction: Individuals with a substance use disorder (SUD) often face barriers to accessing health care, resulting in unmet needs and delayed care. Hospital-based services have the potential to engage individuals with a SUD in ongoing treatment, but there is limited literature characterising this population.

Methods: The Outcomes for Patients Accessing Addiction Care study was a prospective hospital-based cohort study conducted at St.

View Article and Find Full Text PDF

With Medicare Advantage (MA) enrollment surpassing 50 percent of Medicare beneficiaries, accurate risk-adjusted plan payment rates are essential. However, artificially exaggerated coding intensity, where plans seek to enhance measured health risk through the addition or inflation of diagnoses, may threaten payment rate integrity. One factor that may play a role in escalating coding intensity is health risk assessments (HRAs)-typically in-home reviews of enrollees' health status-that enable plans to capture information about their enrollees.

View Article and Find Full Text PDF

Hospitalizations represent important opportunities to engage individuals with substance use disorders (SUD) in treatment. For those who engage with SUD treatment in the hospital setting, tailored supports during post-discharge transitions to longitudinal care settings may improve care linkages, retention, and treatment outcomes. We updated a recent systematic review search on post-hospitalization SUD care transitions through a structured review of published literature from January 2020 through June 2023.

View Article and Find Full Text PDF

Astronauts are known to exhibit a variety of immunological alterations during spaceflight including changes in leukocyte distribution and plasma cytokine concentrations, a reduction in T-cell function, and subclinical reactivation of latent herpesviruses. These alterations are most likely due to mission-associated stressors including circadian misalignment, microgravity, isolation, altered nutrition, and increased exposure to cosmic radiation. Some of these stressors may also occur in terrestrial situations.

View Article and Find Full Text PDF

Background: The relationship between healthcare interventions and context is widely conceived as involving complex and dynamic interactions over time. However, evaluations of complex health interventions frequently fail to mobilise such complexity, reporting context and interventions as reified and demarcated categories. This raises questions about practices shaping knowledge about context, with implications for who and what we make visible in our research.

View Article and Find Full Text PDF

This report describes an alternative endovascular approach to iliac branch devices for treatment of an abdominal aortic aneurysm with concomitant bilateral short common iliac aneurysms. The short distance between the renal arteries and internal iliac artery origins made the addition of distal iliac branch devices to the proximal fenestrated stent graft challenging. We elected to perform physician-modified fenestrated branched endovascular repair, using four fenestrations for the visceral and renal arteries and an additional two directional branches for the bilateral internal iliac arteries.

View Article and Find Full Text PDF

Purpose: To form a multifaceted picture of family caregiver economic costs in advanced cancer.

Methods: A multi-site cohort study collected prospective longitudinal data from caregivers of patients with advanced solid tumor cancers. Caregiver survey and out-of-pocket (OOP) receipt data were collected biweekly in-person for up to 24 weeks.

View Article and Find Full Text PDF

Adaptive avian radiations associated with the diversification of bird beaks into a multitude of forms enabling different functions are exemplified by Darwin's finches and Hawaiian honeycreepers. To elucidate the nature of these radiations, we quantified beak shape and skull shape using a variety of geometric measures that allowed us to collapse the variability of beak shape into a minimal set of geometric parameters. Furthermore, we find that just two measures of beak shape-the ratio of the width to length and the normalized sharpening rate (increase in the transverse beak curvature near the tip relative to that at the base of the beak)-are strongly correlated with diet.

View Article and Find Full Text PDF

Gender-stereotyped beliefs develop early in childhood and are thought to increase with age based on prior research that was primarily carried out in Western cultures. Little research, however, has examined cross-cultural (in)consistencies in the developmental trajectory of gender-stereotyped beliefs. The present study examined implicit gender-toy stereotypes among 4- to 9-year-olds ( = 1,013; 49.

View Article and Find Full Text PDF

Importance: Large enrollment growth has been observed in the Medicare Advantage program, but less is known about enrollment patterns among persons with Alzheimer disease and related dementias (ADRD).

Objective: To evaluate patterns in Medicare Advantage enrollment and disenrollment among beneficiaries with or without ADRD.

Design, Setting, And Participants: This cross-sectional study used 6 national data sources between January 1, 2011, and December 31, 2018.

View Article and Find Full Text PDF

Objective: To examine the proportion of healthcare visits are delivered by nurse practitioners and physician assistants versus physicians and how this has changed over time and by clinical setting, diagnosis, and patient demographics.

Design: Cross-sectional time series study.

Setting: National data from the traditional Medicare insurance program in the USA.

View Article and Find Full Text PDF
Article Synopsis
  • The study aimed to determine if additional cadaveric simulation training for orthopaedic trainees results in better radiological and clinical outcomes for patients undergoing hip fracture surgeries, compared to standard training alone.
  • Conducted as a randomized controlled trial across nine NHS hospitals in England, the trial included 33 trainees who were divided into two groups: one receiving cadaveric training and the other receiving standard training.
  • Results showed that trainees who underwent cadaveric training achieved better outcomes in terms of implant positioning (specifically for hemiarthroplasties) and required fewer postoperative blood transfusions, suggesting the benefits of simulation training.
View Article and Find Full Text PDF
Article Synopsis
  • Ankle fracture fixation is often performed by junior trainees, and a study suggests that using cadaveric simulation training enhances their surgical performance.
  • In a trial with 139 ankle fractures fixed by trainee surgeons, those trained with cadavers showed better fracture reduction and used less radiation compared to those with standard training.
  • The study concluded that cadaveric training improved surgical outcomes for ankle fractures, with the implication that this method could be beneficial in surgical education.
View Article and Find Full Text PDF

States are increasingly the focus of health care spending reform efforts given political deadlock at the federal level. Using the Rhode Island All-Payer Claims Database (APCD) from 2016 to 2019, a modified National Uniform Claim Committee (NUCC) provider taxonomy, and the 2021 Restructured BETOS Classification System (RBCS), we evaluate professional spending trends in commercial and Medicaid populations, identify specialties and clinical service categories driving trends, and examine price and volume contributions to spending changes. We found that professional spending from 2016-2019 in Medicaid is increasing faster than professional spending in commercial (5.

View Article and Find Full Text PDF

Bin/Amphiphysin/Rvs (BAR) proteins are known as classical membrane curvature generators during endocytosis. Amphiphysin, a member of the N-BAR sub-family of proteins that contain a characteristic amphipathic sequence at the N-terminus of the BAR domain, is involved in clathrin-mediated endocytosis. Full-length amphiphysin contains a ~ 400 amino acid long disordered linker connecting the N-BAR domain and a C-terminal Src homology 3 (SH3) domain.

View Article and Find Full Text PDF