Publications by authors named "James Florance"

Article Synopsis
  • Calcium-sensing receptors (CaSRs) are critical in regulating calcium levels and hormone release related to calcium metabolism by acting in the kidneys, gut, and bones.
  • Genetic variations, particularly single nucleotide polymorphisms in CaSR genes, can lead to various conditions affecting calcium balance, such as autosomal dominant hypercalciuric hypocalcaemia.
  • A case study highlights a female patient who developed severe kidney issues after treatment for hypocalcaemia in childhood, but post-kidney transplant, her condition improved and she now has stable calcium and phosphate levels.
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In this study, we examined the effect of two creatine monohydrate supplementation regimes on 24-h urinary creatine and methylamine excretion. Nine male participants completed two trials, separated by 6 weeks. Participants ingested 4 x 5 g x day(-1) creatine monohydrate for 5 days in one trial and 20 x 1 g x day(-1) for 5 days in the other.

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