Publications by authors named "James F Hester"
Article Synopsis
- A study using a specific mouse intercross identified a region on chromosome 14 that affects cholesterol absorption based on gender.
- Congenic animal studies showed that this region has multiple genetic factors leading to differing effects on cholesterol absorption in females compared to males.
- Fine-mapping revealed a 6.3 Mb interval, where female subcongenic mice exhibited a 33% reduction in cholesterol absorption, linked to the candidate gene Ctsb, although further analysis suggested Ctsb might not be responsible for the observed effects.
