Probing the solvent-induced tautomerism of a redox-active ureidopyrimidinone.

A ferrocene-functionalised ureidopyrimidinone has been synthesised that can signal the solvent-induced tautomerism of the dimeric 4[1H]-pyrimidinone form to the monomeric 6[1H]-pyrimidinone form.

Polymeric model systems for flavoenzyme activity: towards synthetic flavoenzymes.

We report the synthesis of a water-soluble flavin polymer using ATRP, whereby the oligoethylene glycol backbone provides both a local hydrophobic environment and redox tuning of the flavin moiety typical of flavoenzyme prototypes.

Tuneable side-chain supramolecular polymer.

[reaction: see text] A random copolymer containing 1,5-dialkyloxynaphthalene moieties has been synthesized using atom-transfer radical polymerization. We have shown that this polymer has the ability to form complexes with the tetracationic cyclophane cyclobis(paraquat-p-phenylene) (CBPQT(4+)) and that electrochemical reduction of the cyclophane or the addition of a competing guest for the cavity of the cyclophane results in disassembly of the supramolecular polymer.

The tuneable complexation of gold nanoparticles.

Mixed monolayer protected gold nanoparticles have been fabricated incorporating 1,5-dialkyloxynaphthalene moieties that are capable of forming complexes with the tetracationic cyclophane cyclobis(paraquat-p-phenylene); electrochemical reduction of the cyclophane or the addition of tetrathiafulvalene results in disassembly of the complexes.

Flavin-based [2]rotaxanes.

[reaction: see text] We report the synthesis of flavin-stoppered hydrogen bonded [2]rotaxanes 1 and 2. We also report the electrochemically controllable properties of these systems in solution, and for derivative 2, as an electropolymerized thin film.

A tuneable self-complexing molecular switch.

[reaction: see text] A new self-complexing donor-acceptor system has been synthesized that has the propensity to undergo intramolecular decomplexation under thermal and electrochemical perturbation and upon addition of a competitive guest for the cyclophane's cavity.

The electrochemically-tuneable interactions between flavin-functionalised C60 derivatives and 2,6-diethylamidopyridine.

We report the electrochemically-tuneable interactions between flavin-functionalised C60 derivatives and a diamidopyridine derivative.

Model systems for flavoenzyme activity: a tuneable intramolecularly hydrogen bonded flavin-diamidopyridine complex.

We report the electrochemically tuneable intramolecular hydrogen bonding interactions between a covalently linked flavin-diamidopyridine unit.