A twenty-year experience with endoscopic therapy for symptomatic primary sclerosing cholangitis.

Goals: The current study presents 1 tertiary endoscopy center's 20-year experience using endoscopic therapy to treat patients with symptomatic primary sclerosing cholangitis (PSC).

Background: Endoscopic therapy for patients with PSC and dominant strictures has been used for more than 20 years, but there is concern that instrumenting a sclerotic biliary tree induces risks that outweigh anticipated benefits.

Study: In this retrospective chart review, 117 patients with PSC were identified using ICD-9 codes.