Publications by authors named "James Dornhoffer"

Objective: To evaluate cochlear implant speech perception among patients with sporadic inner ear schwannoma who underwent ipsilateral implantation.

Study Design: Retrospective multi-institutional cohort study.

Setting: Eleven tertiary academic medical centers across Germany, Denmark, and the United States.

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Article Synopsis
  • The study aims to evaluate how different cochlear dose parameters affect hearing outcomes in patients with sporadic vestibular schwannoma (VS) who have serviceable hearing after undergoing stereotactic radiosurgery (SRS).
  • A total of 205 patients were analyzed over a period from 2007 to 2022, revealing that 62% of patients maintained serviceable hearing at 2 years, while this dropped to 15% by 10 years post-treatment.
  • Results showed a significant association between increased minimum cochlear dose and faster decline in hearing, indicating that this dose parameter should be a key consideration in planning radiosurgery for VS patients.
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Objective: To review audiological experiences and early hearing outcomes from the early feasibility study of a fully implanted cochlear implant.

Study Design: Prospective cohort.

Setting: Tertiary academic medical center.

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Article Synopsis
  • - This study compares cochlear implant (CI) outcomes for speech perception in patients with sporadic vestibular schwannoma (VS) treated through observation, radiosurgery, or microsurgery.
  • - Of the 100 patients analyzed, those who underwent microsurgery had poorer speech perception scores compared to those who were observed or treated with radiosurgery, with only 61% achieving open-set speech perception after microsurgery.
  • - The findings suggest that cochlear implants can be beneficial for sporadic VS patients, particularly those managed by observation or radiosurgery, as these groups showed significantly better outcomes in achieving open-set speech perception.
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Objective: Stereotactic radiosurgery (SRS) is increasingly used for small-to-medium-sized sporadic vestibular schwannoma (VS) and is associated with good tumor control and low-risk of adverse radiation-associated events. The exact mechanism of VS tumor control is unknown but may relate to microvascular hyalinization and resultant tumoral ischemia. This study examined associations of microvascular risk factors with outcomes following SRS.

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Article Synopsis
  • This study investigates the effects of starting computer-based auditory training (CBAT) within the first 3 months after cochlear implant (CI) activation on speech recognition and quality of life for new adult CI users.
  • Involving 65 participants, the research found that early CBAT users showed significantly better improvement in speech recognition scores and quality of life measures at the 3-month mark compared to late starters.
  • However, by 12 months postactivation, both early and late users achieved similar benefits, indicating that while early intervention is advantageous, late starters can still catch up over time.
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Objective: To describe the rare process of osteolytic labyrinthitis, previously referred to as labyrinthine sequestrum, which involves progressive obliteration of the bony and membranous labyrinth with eventual supplantation with soft tissue and, in some cases, bony sequestrum.

Patients: Three patients with diverse presentations of osteolytic labyrinthitis from two tertiary care academic medical centers.

Interventions: Case series report analyzing the relevant clinical, radiologic, pathologic, and surgical data on our patients with osteolytic labyrinthitis and comparing these index cases to the existing literature.

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Objective: To examine current practices and opinions of cochlear implant (CI) providers with respect to post-implantation auditory training.

Methods: A survey was submitted to the American Cochlear Implant Alliance membership that reviewed current practice and opinions with respect to post-implantation auditory training for adult CI recipients.

Main Outcome Measures: Review of respondent practice, center volume, role on CI team, and current usage and opinions surrounding auditory training, including resources used and schedule of use.

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Objective: To present a method for repair of the stapedial and tensor tympani tendons in a patient with hyperacusis after a tendon lysis procedure.

Patients: A 71-year-old professional musician who presented to clinic with debilitating hyperacusis following a tensor tympani and stapedial tendon lysis procedure to treat middle ear myoclonus.

Interventions: A novel procedure for reapproximation of the tensor tympani and stapedial tendons into their native insertion points using periosteal grafts and nitinol wire.

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Objective: To describe the experience and results from coordinated and closely scheduled radiosurgery and cochlear implantation (CI) in a vestibular schwannoma (VS) cohort.

Patients: Patients with VS who underwent radiosurgery followed by CI on the same or next day.

Interventions: Interventions included sequential radiosurgery and CI.

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Objective: The process of adapting to communicate with a cochlear implant (CI) is complex. The use of auditory training after cochlear implantation may help to facilitate improvements in postoperative speech recognition and quality-of-life outcomes in new adult CI recipients. However, the effectiveness of auditory training remains uncertain and long-term effects have not been examined in a large sample of new adult CI users.

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Article Synopsis
  • - The study aimed to evaluate how effective auditory training is for adults with cochlear implants by following PRISMA guidelines and analyzing various research databases for relevant literature as of June 2023.
  • - Research focused on studies that involved adult patients, training methods, and measures of speech recognition or patient feedback, while excluding those that involved children or isolated forms of training.
  • - Out of 23 reviewed studies, most showed positive results from auditory training, with patient-directed training significantly enhancing vowel and speech recognition in noise, and clinician-directed training improving sentence recognition in noise; however, the overall body of literature is limited and varied in quality.
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Objectives: A small number of cochlear implant (CI) users experience facial nerve stimulation (FNS), which can manifest as facial twitching. In some patients, this can be resolved by adjusting the electrical stimulation parameters. However, for others, facial stimulation can significantly impair CI outcomes or even prevent its use.

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Purpose: Radiographic review of pathologies that associate with third window syndrome.

Methods: Case series and literature review.

Results: Eight unique third window conditions are described and illustrated, including superior, lateral, and posterior semicircular canal dehiscence; carotid-cochlear, facial-cochlear, and internal auditory canal-cochlear dehiscence, labyrinthine erosion from endolymphatic sac tumor, and enlarged vestibular aqueduct.

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Background And Objectives: The infratemporal fossa (ITF) is a complex region bounded by the temporal bone, maxilla, sphenoid, pterygoid plates, and mandibular ramus. Containing a high density of neurovascular and musculoskeletal structures, the ITF can house a number of pathologies, and access is challenging. The ITF approach and its variations can be challenging due to complex anatomy and unfamiliarity by many surgeons.

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Objective: The objective of the current study was to present the results of an international working group survey identifying perceived limitations of existing facial nerve grading scales to inform the development of a novel grading scale for assessing early postoperative facial paralysis that incorporates regional scoring and is anchored in recovery prognosis and risk of associated complications.

Study Design: Survey.

Setting: A working group of 48 multidisciplinary clinicians with expertise in skull base, cerebellopontine angle, temporal bone, or parotid gland surgery.

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Objective: To compare cochlear implant (CI) and auditory brainstem implant (ABI) performance in patients with NF2-related schwannomatosis (NF2).

Study Design: Historical cohort.

Setting: Tertiary academic center.

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Objective: Comprehensively assess the prevalence of monopolar electrosurgery-related device complications among cochlear implant (CI) recipients.

Study Design: Multifaceted retrospective review and survey.

Setting: Tertiary medical center.

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Cochlear implantation has become the standard of care for the treatment of moderate-to-profound bilateral sensorineural hearing loss. However, current technologies, all of which rely on an external sound processor, have intrinsic limitations that prevent certain activities and diagnostics, thus hampering full integration into a patient's lifestyle. The Envoy Medical (White Bear Lake, MN, USA) Acclaim fully implanted cochlear implant is a new device currently undergoing testing that has been designed to alleviate many of the current constraints by housing all components within the patient, thus allowing for near-constant use in many environments that are not conducive to a traditional cochlear implant.

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No standard schedule for cochlear implant (CI) programming has been developed, and common practices may have CI recipients seen in excess of what is necessary. The objective of this study was to review evidence for a de-escalated, evidence-based schedule for adult CI programming. Systematic review was undertaken in March 2023 of PubMed, Scopus, and CINAHL databases using the Preferred Reporting Items for Systemic Reviews and Meta-analyses (PRISMA) guidelines.

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Background And Objectives: Vestibular schwannomas (VS) are often phenotypically benign lesions that may be technically challenging to resect because of involvement of neurovascular structures. The anterior inferior cerebellar artery (AICA) is commonly identified near VS, with variable position in relation to the tumor; however, little published literature describes anatomic and pathologic variants of AICA observed during VS resection.

Methods: A prospectively maintained cohort of surgically managed VS with available operative reports and clinical/radiographic follow-up was queried and reviewed for noted aberrations.

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Objective: Compare cochlear implant (CI) performance between patients with ipsilateral sporadic vestibular schwannoma (VS) and NF2-related schwannomatosis (NF2). Compare CI performance according to VS management modality.

Study Design: Historical cohort.

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Objective: To report 20 years of natural history data for a facial paraganglioma and provide a comprehensive review of the existing literature.

Patient: 81-year-old female with a remote history of cardiac arrest while under anesthesia who elected to observe her facial paraganglioma for 20 years.

Interventions: Observation, clinical documentation, radiographic surveillance.

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Objective: The use of computer-based auditory training (CBAT) after cochlear implantation is associated with improved speech recognition and real-world functional abilities. However, patient-related factors associated with CBAT use remain unknown. This study seeks to identify such factors and recognize those at risk for not implementing CBAT.

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