Intravenous Tranexamic Acid Given at Femoral Fragility Fracture Surgery Reduces Blood Transfusion Requirements Fourfold.

Aims: This study aims to determine whether intraoperative intravenous (IV) tranexamic acid (TXA) affects blood loss following the surgical management of femoral fragility fractures (FFF).

Methods: This was a single centre (university teaching hospital) non-randomised case-control study. There were 361 consecutive patients with FFF admitted over a 4-month period were included (mean age 81.

Risk factors for antimicrobial resistance in patients with bacteraemia related to urinary tract infection.

Introduction: NHS Lothian policy has recently changed to avoid first-line use of trimethoprim for uncomplicated urinary tract infections (UTI) in patients with risk factors for trimethoprim resistance, in line with national guidance. This study aimed to identify risk factors for antimicrobial resistance in bacteraemia related to UTI.

Methods: A retrospective cohort study of 687 patients with bacteraemia related to UTI in NHS Lothian from 01/02/18 to 29/02/20 was undertaken.