Publications by authors named "James B Badenoch"
Neuroanatomical and prognostic associations of depression in Parkinson's disease.
J Neurol Neurosurg Psychiatry
September 2024
Background: Depression is reported as a risk factor, prodromal feature and late consequence of Parkinson's disease (PD). We aimed to evaluate the timing, neuroanatomy and prognostic implications of depression in PD.
Methods: We used data from 434 023 participants from UK Biobank with 14.
Background And Purpose: This review aims to characterize the pattern of post-COVID-19 cognitive impairment, allowing better prediction of impact on daily function to inform clinical management and rehabilitation.
Methods: A systematic review and meta-analysis of neurocognitive sequelae following COVID-19 was conducted, following PRISMA-S guidelines. Studies were included if they reported domain-specific cognitive assessment in patients with COVID-19 at >4 weeks post-infection.
Article Synopsis
- This study looked at how mental health issues like depression and anxiety affect people with Parkinson's disease and how these issues relate to their overall health and well-being.
- Researchers examined many studies to find out if having these mental health problems makes Parkinson's symptoms worse, which can include things like memory problems and falling.
- They found a lot of evidence showing that problems like psychosis are linked to worse outcomes in Parkinson's patients, indicating that mental health is really important for their overall condition.
Background: Neuropsychiatric presentations of monkeypox (MPX) infection have not been well characterised, despite evidence of nervous system involvement associated with the related smallpox infection.
Methods: In this pre-registered (PROSPERO ID 336649) systematic review and meta-analysis, we searched MEDLINE, EMBASE, PsycINFO, AMED and the preprint server MedRxiv up to 31/05/2022. Any study design of humans infected with MPX that reported a neurological or psychiatric presentation was included.
Article Synopsis
- A systematic review and meta-analysis was conducted to determine the prevalence of neuropsychiatric symptoms in COVID-19 survivors, examining 51 studies and over 18,000 patients.
- The most common symptoms identified were sleep disturbances (27.4%), fatigue (24.4%), cognitive impairment (20.2%), anxiety (19.1%), and post-traumatic stress (15.7%).
- Despite high study heterogeneity, findings suggest that neuropsychiatric symptoms are prevalent and persistent after COVID-19, with limited differences based on hospitalization or severity of illness.