Publications by authors named "James Aoina"
Article Synopsis
- - The study investigates the effectiveness of tranexamic acid (TXA) for reducing blood loss during total knee arthroplasty (TKA), comparing topical and systemic administration methods in a randomized controlled trial with 134 patients.
- - Both topical (tTXA) and systemic (sTXA) TXA routes significantly reduced estimated perioperative blood loss compared to a placebo group, with no notable difference in blood loss between the two TXA methods.
- - The findings suggest that a single intraoperative dose of 1.5 g of TXA, whether given topically or systemically, is effective for minimizing blood loss in TKA patients without increasing complication rates.
Purpose: This study aimed to determine whether sedentary overweight subjects with type 2 diabetes have impaired diastolic function compared with equally sedentary and overweight nondiabetic subjects.
Methods: Mitral valve pulsed Doppler echocardiography and tissue Doppler imaging (TDI) were used to assess left ventricular structure and diastolic function in 40- to 60-yr-old sedentary overweight subjects with type 2 diabetes (N = 13) and age- and body mass-matched sedentary nondiabetic subjects (N = 15). Pseudonormal filling was identified using preload reduction and TDI.
Maximal O(2) consumption (Vo(2 max)) is lower in individuals with Type 2 diabetes than in sedentary nondiabetic individuals. This study aimed to determine whether the lower Vo(2 max) in diabetic patients was due to a reduction in maximal cardiac output (Q(max)) and/or peripheral O(2) extraction. After 11 Type 2 diabetic patients and 12 nondiabetic subjects, matched for age and body composition, who had not exercised for 2 yr, performed a bicycle ergometer exercise test to determine Vo(2 max), submaximal cardiac output, Q(max), and arterial-mixed venous O(2) (a-v O(2)) difference were assessed.
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