The determination of occupational exposure to polycyclic aromatic hydrocarbons by the analysis of 1-hydroxypyrene in urine using a simple automated online column switching device and high-performance liquid chromatography.

An analytical method using a liquid chromatograph combined with a simple online column switching sample pre-treatment system was developed for the determination of 1-hydroxypyrene (1-HP) in urine. This compound is the metabolite of pyrene and is used to assess the exposure of workers to polycyclic aromatic hydrocarbons (PAHs). After enzymatic hydrolysis, a urine sample was directly injected into a high-performance liquid chromatograph (HPLC) where it automatically underwent a sample cleanup using a column switching device.

Determination of quartz in bulk materials from workplace environments using X-ray diffractometry and the absorption diffraction method.

A method is described for the determination of crystalline quartz in bulk materials from workplace environments as part of occupational hygiene investigations using X-ray powder diffractometry. The absorption-diffraction model was used for quantification with mass absorption coefficients for samples being experimentally determined using an absorption cell placed in front of the diffracted beam anti-scatter slit. The method was found to be reliable for samples containing from 0.