Publications by authors named "Jamal Badir"
The coronavirus pandemic, which appeared in Wuhan, China, in December 2019, rapidly spread all over the world in only a few weeks. Faster testing techniques requiring less resources are key in managing the pandemic, either to enable larger scale testing or even just provide developing countries with limited resources, particularly in Africa, means to perform tests to manage the crisis. Here, we report an unprecedented, rapid, reagent-free and easy-to-use screening spectroscopic method for the detection of SARS-CoV-2 on RNA extracts.
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- Objective
- : The study focused on analyzing ESBL-producing E. coli from patients with infections at a Moroccan hospital due to the rising global concern about these bacteria and the lack of genomic data in North Africa.
- Methods
- : Researchers used whole-genome sequencing on 18 E. coli isolates to investigate their evolution, virulence, and resistance genes, comparing them with strains from neighboring countries.
- Results
- : Most isolates were identified as ST131, indicating a significant pandemic clone with many virulence genes, while all isolates had antibiotic resistance traits, but none had carbapenemase genes, suggesting a specific risk profile for the region.
Background: Pyrosequencing Allele Quantification (AQ) is a cost-effective DNA sequencing method that can be used for detecting somatic mutations in formalin-fixed paraffin-embedded (FFPE) samples. The method displays a low turnaround time and a high sensitivity. Pyrosequencing suffers however from two main drawbacks including (i) low specificity and (ii) difficult signal interpretation when multiple mutations are reported in a hotspot genomic region.
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- Ebola virus disease (EVD) is highly fatal, and during the 2014 outbreak, the WHO identified favipiravir as a potential treatment, but ethical concerns prevented randomized trials.
- Instead, a multicenter non-randomized trial was conducted where all patients received favipiravir to assess its feasibility, safety, and effectiveness in treating EVD.
- Participants were selected based on specific criteria and received a set dosage of favipiravir, with the goal of gathering preliminary data to inform future research rather than establish definitive treatment guidelines.
Aim To clarify whether applying alpha-methyldopa treatment influences flow resistance in umbilical cord artery in pregnant women suffering from hypertensive disorder. Methods In this prospective cross-sectional study a follow-up was done for 50 pregnant women with singleton pregnancies between 36 and 40 gestation weeks, who had been hospitalized at the Gynecology and Obstetrics Department of the Cantonal Hospital Zenica, Bosnia and Herzegovina from October 2009 to January 2012. Pregnant women were classified in two groups according to the level of using alpha-methyldopa in the treatment.
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