Efficacy of liposomal amphotericin B in treating fungal meningitis in AIDS Patients: A review article.

Cryptococcal meningitis is an alarming fungal infection that usually affects the meninges surrounding the brain and spinal cord. The causative organism is Cryptococcus neoformans. Although this infection can occur in normal individuals, it is more often seen in patients with human immunodeficiency virus/acquired immunodeficiency syndrome.

Modern Digital Query Analytics of Patient Education Materials on Acanthosis Nigricans: Systematic Search and Content Analysis.

Background: Online digital materials are integral to patient education and health care outcomes in dermatology. Acanthosis nigricans (AN) is a common condition, often associated with underlying diseases such as insulin resistance. Patients frequently search the internet for information related to this cutaneous finding.

Factors associated with attention deficit hyperactivity disorder symptoms among patients with substance use in Malaysia.

Background: Attention deficit hyperactivity disorder (ADHD) often coexists with substance use disorders (SUDs). This study aimed to determine factors associated with ADHD symptoms among adults with SUDs in Malaysia.

Methods: Patients aged ≥18 years with a ≥1-year history of substance use who were admitted to any of the three drug rehabilitation centres in urban Malaysia for >1 month were invited to participate.

Facile synthesis of nanoporous Mg crystalline structure by organic solvent-based reduction for solid-state hydrogen storage.

Nanoporous metals have unique potentials for energy applications with a high surface area despite the percolating structure. Yet, a highly corrosive environment is required for the synthesis of porous metals with conventional dealloying methods, limiting the large-scale fabrication of porous structures for reactive metals. In this study, we synthesize a highly reactive Mg nanoporous system through a facile organic solution-based approach without any harsh etching.

Association Between Sleep Duration and Cardiovascular Disease Among Asian Americans.

Background: Cardiovascular disease (CVD) prevalence varies widely among Asian American adults. The American Heart Association added healthy sleep to its metrics to define ideal cardiovascular health. Little is known about the association between sleep and CVD prevalence among Asian subgroups.

Pathological roles of lncRNA HOTAIR in liver cancer: An updated review.

Liver cancer ranks as the sixth most prevalent form of cancer and stands as the fourth leading cause of cancer-related fatalities on a global scale. The two primary types of liver cancer are hepatocellular carcinoma (HCC) and intrahepatic cholangiocarcinoma (ICC). While ICC originates from the bile ducts, HCC develops from hepatocytes, which are the primary functional cells of the liver.

Frequency of Acute Kidney Injury in Patients Admitted With Acute Stroke at Hayatabad Medical Complex, Peshawar.

Background Patients hospitalized with acute stroke are at risk of developing acute kidney injury (AKI), and when both conditions occur together, patient outcomes are often worse. The relationship between stroke type, patient characteristics, and the development of AKI is not fully understood, particularly in tertiary care settings in Pakistan, where healthcare resources and patient characteristics may differ from Western populations. Objective To determine the frequency of AKI and identify associated risk factors, including stroke type, severity, and comorbidities, in patients presenting with acute stroke at a tertiary care center in Pakistan, the Hayatabad Medical Complex, Peshawar.

IoT based real-time water quality monitoring system in water treatment plants (WTPs).

This study presents the development and implementation of an Internet of Things (IoT)-based real-time water quality monitoring system tailored for water treatment plants (WTPs). The system integrates advanced sensor technologies to continuously monitor key water quality parameters such as pH, dissolved oxygen (DO), total dissolved solids (TDS), and temperature. Data collected by these sensors is transmitted through a robust communication network to a centralized monitoring platform that utilizes cloud-based storage and analytics.

Continuous Flow Photoelectrochemical Reactor with Gas Permeable Photocathode: Enhanced Photocurrent and Partial Current Density for CO Reduction.

Photoelectrochemical (PEC) CO reduction using a photocathode is an attractive method for making valuable chemical products due to its simplicity and lower overpotential requirements. However, previous PEC processes have often been diffusion-limited leading to low production rates of the CO reduction reaction, due to inefficient gas diffusion through the liquid electrolyte to the catalyst surface, particularly at high current densities. In this study, a gas-permeable photocathode in a continuous flow PEC reactor is incorporated, which facilitates the direct supply of CO gas to the photocathode-electrolyte interface, unlike dark reaction-based flow reactors.

Techno-economic assessment and innovative production of nutrient-rich jam, jelly, and pickle from Sonneratia apetala fruit.

Sonneratia apetala, a nutrient-rich mangrove fruit, presents an opportunity for innovative food product development, offering potential health benefits and economic value through the creation of jam, jelly, and pickle. This innovative invention reveals the nutritional content including vitamins and minerals of Sonneratia apetala jam, jelly, and pickles from Nijhum Dwip in Hatiya Upazila, Noakhali District. These products contain Na, Mg, K, Ca, Mn, Fe, Cu, and Zn, which are essential for human nutrition.

Deciphering supramolecular arrangements, micellization patterns, and antimicrobial potential of bacterial rhamnolipids under extreme treatments of temperature and electrolyte.

The micellization properties of rhamnolipids (RLs) in extreme electrolyte concentrations and temperatures have gained considerable attention due to their broad industrial applications. In this study, the aggregation behavior, specifically the micellization pattern (critical micelle concentration (CMC)) of RLs produced from a newly isolated thermophilic strain of from a harsh environment of an oil field, was investigated by a spectrophotometric method at various temperatures (293-393 K) and electrolyte concentrations (NaCl: 2-20%). The result indicated that the values (0.

Green Synthesis, Characterization and Pharmaceutical Applications of Biocompatible Zinc Oxide Nanoparticles Using Stocks.

Zinc oxide nanoparticles are safe, non-toxic, and biocompatible. These NPs are used in food packaging materials, self-cleaning glass, ceramics, deodorants, sunscreens, paints, coatings, ointments, lotions, and as preservatives. This study explored the biological potential of ZnO nanoparticles synthesized using .

Readability Metrics in Patient Education: Where Do We Innovate?

The increasing use of digital applications in healthcare has led to a greater need for patient education materials. These materials, often in the form of pamphlets, booklets, and handouts, are designed to supplement physician-patient communication and aim to improve patient outcomes. However, the effectiveness of these materials can be hindered by variations in patient health literacy.

Feasibility and Acceptability of Universal Adult Screening for Chronic Hepatitis B in Primary Care Clinics.

Introduction: Two thirds of Americans infected with chronic hepatitis B are unaware of their infection. In March 2023, the Centers for Disease Control and Prevention recommended moving from risk-based to universal adult chronic hepatitis B screening. In April 2022, Stanford implemented chronic hepatitis B universal screening discussion alerts for primary care providers.

Nitric oxide application alleviates fungicide and ampicillin co-exposure induced phytotoxicity by regulating antioxidant defense, detoxification system, and secondary metabolism in wheat seedlings.

Pesticides and antibiotics usually sink into soil, posing serious phytotoxic effects on plants. However, studies are elusive regarding the phytotoxic effects of fungicide Consento (CON) and antibiotic ampicillin (AMP) co-exposure. Nitric oxide (NO) is an important plant signaling molecule known for abiotic stress tolerance in plants.

Exploring online health resources and self-care among irritable bowel syndrome patients: analyzing internet use and AI chatbot interactions.

Background: The increasing prevalence of irritable bowel syndrome (IBS) in Saudi Arabia has led to a growing interest in understanding how patients seek health information online. While it is known that digital platforms, such as search engines, social media, and artificial intelligence (AI) chatbots, are commonly used for health information seeking, there is limited knowledge about the specific behaviors of IBS patients in this context and how these behaviors correlate with their self-care activities. This study aimed to explore online health information-seeking behavior and its correlation with self-care activities among patients with IBS in Saudi Arabia, focusing on the use of these digital platforms.

Healthcare workers' knowledge and preparedness for unprecedented foodborne botulism outbreak in Saudi Arabia.

Background: The recent unprecedented foodborne botulism outbreak in Saudi Arabia necessitated an assessment of healthcare workers' (HCWs) knowledge, attitudes, and practices (KAP). This study assessed healthcare workers' knowledge regarding the transmission, contagiousness, presentation, and diagnosis of foodborne botulism, as well as their management practices, including contacting public health authorities, administering antitoxin, preparedness to respond to botulism cases and consulting generative Artificial Intelligent (AI)-chatbots, like ChatGPT.

Methods: A cross-sectional online survey targeting Saudi HCWs was conducted from May 6-19, 2024, following the first foodborne botulism outbreak.

Autoantibodies directed against interferon alpha, nuclear antigens, cardiolipin, and beta 2 glycoprotein 1 are not induced by SARS-CoV-2 or associated with long COVID.

Introduction: Autoantibodies (AAbs) directed against interferon alpha (aIFNα), nuclear antigens (ANAs), anti-cardiolipin (aCL), and anti-beta 2 glycoprotein 1 (aβ2GP1), have been demonstrated to significantly correlate with the severity of acute Coronavirus Disease 2019 (COVID-19). However, whether severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection induces these AAbs and whether they are associated with long COVID remains unclear.

Methods: The potential induction of aIFNα, ANAs, aCL, and aβ2GP1 by SARS-CoV-2 was assessed by measuring these AAbs in 224 pre- and post-infection paired serum samples from the Johns Hopkins Hospital Emergency Department (JHHED).