Publications by authors named "Jalon Jones"
Background: Chronic pain, defined as pain persisting for more than 3-6 months, has a mean one-year prevalence in the United States of 25.8% and is one of the most frequent reasons adults seek medical care. Treatment options include physical therapy, analgesics, anticonvulsants, exercise, and muscle relaxants.
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- The study investigates the effectiveness of different suturing techniques (non-absorbable nylon, absorbable vicryl, and fibrin glue) in nerve grafting for rats with sciatic nerve injuries.
- Results show that both vicryl and nylon sutures improved motor function significantly more than controls, with no major differences in nerve recovery overall among the different methods.
- The findings suggest that vicryl sutures are equally effective as nylon sutures for nerve repair, challenging the previous notion that non-absorbable sutures are superior.
Medical research on neurologic ailments requires representative animal models to validate treatments before they are translated to human clinical trials. Rodents are the predominant animal model used in neurological research despite limited anatomic and physiologic similarities to humans. As a result, functional testing designed to assess locomotor recovery after neurologic impairment is well established in rodent models.
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