Publications by authors named "Jalene Magee"
High-throughput detection of glutathione s-transferase polymorphic alleles in a pediatric cancer population.
Cancer Epidemiol Biomarkers Prev
February 2004
Article Synopsis
- Polymorphisms in GST enzymes can affect cancer risk and the effectiveness of chemotherapy.
- A new PCR-based high-throughput genotyping assay has been developed that is cost-effective and reliable for large clinical trials.
- The study shows a strong correlation between certain GST gene variants and an increased risk of specific cancers like acute lymphoblastic leukemia and osteosarcoma.