Effects of Physical Forms of Total Mixed Rations on Intake, Weaning Age, Growth Performance, and Blood Metabolites of Crossbred Dairy Calves.

This study evaluated the effects of hay-based total mix ration (TMR) in pelleted or unpelleted form on intake, weaning age, performance parameters, blood metabolites, and cost-effectiveness in crossbred dairy calves during the preweaning period under hot climatic conditions. Thirty calves (4 ± 1 days (d) old), were assigned to one of the three dietary treatments in a randomized complete block design. Treatments assigned were: (1) conventional calf starter (CCS); without hay (2) TMR containing 85% calf starter and 15% chopped oat hay (OH) and (3) pelleted TMR (PTMR) containing 85% calf starter and 15% OH.

Advancement in multifunctional nanoparticles for the effective treatment of cancer.

Introduction: Nanotechnology has gained wider importance for the treatment of various diseases, including cancer. Multifunctional or theranostic agents are emerging as promising therapeutic paradigms, which provide attractive vehicles for both image and therapeutic agents. Nanosystems are capable of diagnosis, specific targeted drug therapy and monitoring therapeutic response.

Insight into the biomarkers as the novel anti-psoriatic drug discovery tool: a contemporary viewpoint.

Psoriasis is a common chronic autoimmune skin disorder with T-cell mediated multifunctional complex pathogenesis along with genetic predisposition. Conventionally, many therapies are available for the management of psoriasis, but they have limited efficacy due to higher side effects. Over the last decade, one of the major efforts in psoriasis research has been made for the development of drug molecules by understanding the potential biomolecules/biomarkers associated with psoriasis.