Protective effects of coenzyme Q and L-carnitine against statin-induced pancreatic mitochondrial toxicity in rats.

Statins are widely used in patients with hyperlipidemia and whom with high risk of cardiovascular diseases. Unfortunately, statins also exert some adverse effects on the liver and pancreas and enhance the risk of type 2 diabetes mellitus. The objective of the present research was to investigate the protective effects of coenzyme Q (Co-Q) and L-carnitine (LC) on statins induced toxicity on pancreatic mitochondria .