MicroRNA 155 Downregulation by Vitamin C-Loaded Human Serum Albumin Nanoparticles During Cutaneous Wound Healing in Mice.

This study focused on potential of vitamin C loaded human serum albumin (HSA) nanoparticles for treatment of wound. Nanocarrier were prepared and assessed for their effect on growth of 3T3 fibroblast cells, cell migration, wound healing rate and expression of miR-155, TGF-β1 and SMAD 1,2 genes. Wound healing assay was done and wounds were treated with vitamin C loaded HSA nanoparticles.

Investigation of antimicrobial effects of treated larvae extract on bacteria.

Background And Objectives: Larval therapy refers to the use of larvae on chronic wounds, which is a successful method of chronic wounds treatment. The secretions of these larvae contain antibacterial compounds and lead to death or inhibition of bacterial growth.

Materials And Methods: In this study, we investigated the antibacterial effects of larvae secretions which were in sterilized and multi antibiotic-resistant bacteria-treated forms on Gram-positive bacteria and Gram-negative bacteria.