Publications by authors named "Jalal Mosayebi Amroabadi"
Elevated CDK5R1 expression associated with poor prognosis, proliferation, and drug resistance in colorectal and breast malignancies: CDK5R1 as an oncogene in cancers.
Chem Biol Interact
December 2022
Background: Studies have shown that the CDK5R1 gene could have a part in some types of cancer. This study sought to examine the relationship between CDK5R1 expression and prognosis and medication resistance in 13 commonly occurring cancers.
Method: The cancer genome atlas data and clinical data were utilized to assess the role of CDK5R1 in malignancies.
Background: The tripartite motif containing (TRIM)-22 participates in innate immune responses and exhibits antiviral activities. The present study aimed to assess of the relationship between TRIM22 single-nucleotide polymorphisms and clinical parameters with the coronavirus disease 2019 (COVID-19) infection severity.
Methods: TRIM22 polymorphisms (rs7113258, rs7935564, and rs1063303) were genotyped using TaqMan polymerase chain reaction (PCR) assay in 495 dead and 497 improved severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)-positive patients.
Article Synopsis
- - The study investigated the presence of Acanthamoeba polyphaga mimivirus (APMV) in respiratory samples from patients suspected of having tuberculosis (TB) over a four-year period, analyzing 10,166 samples.
- - Out of the analyzed samples, 4 patients (0.04%) tested positive for Mimivirus, with most being in the ICU and having underlying health issues.
- - The findings suggest a possible link between Mimivirus and pneumonia, indicating the need for further research on the clinical significance of Mimivirus infections in various regions.
Background: The recent pandemic caused by severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) has elevated several clinical and scientific questions. These include how host genetic factors influence the pathogenesis and disease susceptibility. Therefore, the aim of this study was to evaluate the impact of interferon lambda 3 and 4 (IFNL3/4) gene polymorphisms and clinical parameters on the resistance and susceptibility to coronavirus disease 2019 (COVID-19) infection.
View Article and Find Full Text PDFMerkel cell polyomavirus (MCPyV) infects most people asymptomatically, but recent reports indicate that the virus may be related to carcinogenesis. This study aimed to evaluate the impact of MCPyV on the development of papillary thyroid cancer (PTC). Totally, 1057 samples, including 412 fresh biopsy samples (FBS) and 645 paraffin-embedded PTC biopsy samples (PEBS), and 1057 adjacent non-cancerous samples were assessed for the presence of MCPyV DNA and RNA.
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