Publications by authors named "Jalal Jafarzadeh"
Article Synopsis
- - The study focuses on the head louse, Pediculus humanus capitis, which is a significant public health concern globally, particularly in northern Iran, where genetic analysis is key for managing infestations.
- - Researchers collected adult head lice from 100 infested individuals across five regions in Mazandaran Province and analyzed their mitochondrial DNA, discovering two genetic clades (A and B) and identifying 13 haplotypes.
- - Clade A was the most prevalent, representing 75% of samples, and the findings indicated high genetic diversity among the lice populations, with 11 of the haplotypes being previously unknown.
Article Synopsis
- * In a study with 114 migraine patients and 114 healthy controls, 53.5% of migraine patients tested positive for Toxoplasma antibodies, pointing to a 90% higher risk of migraines among those infected.
- * The analysis of the MMP-9 genetic polymorphism revealed a significant prevalence of certain genotypes in migraine patients, suggesting that variations in the MMP-9 gene may influence migraine pathology in the context of Toxoplasma infection.
Article Synopsis
- The COVID-19 pandemic may contribute to delays in diagnosing serious illnesses like oral squamous cell carcinoma and worsen the management of patients with pre-existing health issues and oral lesions, including oral candidiasis, a common COVID-19 symptom.
- An 83-year-old female patient diagnosed with oral carcinoma developed oropharyngeal candidiasis after recovering from COVID-19 pneumonia, experiencing painful symptoms like difficulty swallowing and speaking.
- The study highlights a high risk of fungal infections in severe COVID-19 cases affecting the oral mucosa, though it's unclear if these infections are directly related to COVID-19 itself or other factors.
Background: The aim of the present study was to compare the epidemiological patterns of severe acute respiratory syndrome coronavirus 2 (SARS-CoV2) infections, hospitalizations, deaths, and duration of hospitalization during the fourth, fifth and sixth epidemic waves of coronavirus disease 2019 (COVID-19) in Iran.
Methods: A multicenter retrospective observational study was conducted on hospitalized patients in four hospitals in the Babol district of northern Iran. The study periods were during the fourth, fifth, and sixth waves of the epidemic in Iran, (March 2021 to March 2022).
Background: Toxoplasmosis is a cosmopolitan parasitic infection caused by Toxoplasma gondii which is commonly treated by pyrimethamine (PYR) plus sulfadiazine (SDZ) with several adverse side effects. The present study evaluated the therapeutic effects of Urtica dioica L. aqueous extract (UDE) on acute and chronic toxoplasmosis in mice.
View Article and Find Full Text PDFBackground And Purpose: Given the high mortality rate of invasive candidiasis in hospitalized pediatric patients, it is crucial to establish a predictive system to achieve early diagnosis and treatment of patients who are likely to benefit from early antifungal treatment. This study aimed to assess the colonization index, species distribution, and antifungal susceptibility pattern of strains isolated from pediatric patients with high colonization index (CI).
Materials And Methods: This study was carried out at the Children's Medical Center in Tehran-Iran.
Background And Purpose: This study aimed to evaluate the species distribution and susceptibility pattern of the strains isolated from Candida colonization in pediatric patients staying at pediatric intensive care unit (ICU) and infant ICU of Children's Medical Center in Tehran, Iran.
Materials And Methods: This study was conducted in the Children's Medical Center in Tehran, Iran. In total, 440 samples from 56 patients with oral cavity, skin surrounded catheters, and ear, throat, nasal, and urine cultures were collected.
Article Synopsis
- Invasive mucormycosis is a serious fungal infection that often occurs in diabetic patients, especially those with COVID-19 due to treatment with corticosteroids, leading to higher risks of mortality.
- A case study in Iran involved a 73-year-old diabetic woman with COVID-19 who developed rhino-orbital mucormycosis after receiving treatment for her lung issues.
- Histopathology confirmed the presence of the infection, and with timely antifungal treatment, the patient responded well, marking this as the first documented case in Iran related to COVID-19.
sections and comprise clinically relevant and cryptic species that differ significantly in drug susceptibility, meaning that effective treatment depends on correct species identification. There are no comprehensive data for molecular identification and antifungal susceptibility testing (AFST) of clinically relevant and cryptic species of sections and as the main agents of invasive and non-invasive aspergillosis in Iran. We aimed to perform molecular identification and AFST of 213 clinical isolates belonging to sections and .
View Article and Find Full Text PDFArticle Synopsis
- A new pathogenic yeast has gained attention for its rapid spread and resistance to multiple drugs, often causing hospital outbreaks and being misidentified by traditional methods.
- The report details the first case of fluconazole-resistant otitis in an immunocompetent patient in Iran, showing a high resistance level to the drug yet successfully treated with alternative medications.
- This case marks the second instance of a fluconazole-resistant yeast strain found in otitis in Iran, differing from the earlier strain identified.
The fungus genus Neoscytalidium is mainly distributed in (sub) tropical regions of the world and has been essentially considered as a phytopathogen. There are however several reports of human infection caused by Neoscytalidium spp. through direct or indirect contact with contaminated plants or soil.
View Article and Find Full Text PDFRecurrent vulvovaginal candidiasis (RVVC) is one of the most prevalent fungal infections in humans, especially in developing countries; however, it is underestimated and regarded as an easy-to-treat condition. RVVC may be caused by dysbiosis of the microbiome and other host-, pathogen-, and antifungal drug-related factors. Although multiple studies on host-related factors affecting the outcome have been conducted, such studies on -derived factors and their association with RVVC are lacking.
View Article and Find Full Text PDFBackground: Several previous studies have shown cavitary lung lesions in old pulmonary tuberculosis (PTB) increase the risk of fungus ball. Detection of galactomannan (GM) in bronchoalveolar lavage (BAL) is also proposed as a diagnostic approach for the fungus ball.
Objectives: We evaluated the diagnosis of fungus balls and GM levels in BAL samples in PTB patients.
In this present study, for the first time, we evaluated the cystic fibrosis (CF) patients for the Scedosporium species and their antifungal susceptibility against eight antifungal agents. During one-year period, 90 Sputum samples were collected from Iranian CF patients. All samples were evaluated by direct microscopic examination, culture onto four different media including Malt extract agar, Inhibitory mold agar, Brain Heart Infusion and Scedo-Select III.
View Article and Find Full Text PDF