Publications by authors named "Jakob Hufschmidt"
Chronic traumatic encephalopathy (CTE) is a neurodegenerative disease associated with exposure to repetitive head impacts. CTE has been linked to disruptions in cognition, mood, and behavior. Unfortunately, the diagnosis of CTE can only be made post-mortem.
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- The study evaluated changes in brain white matter diffusion characteristics in collegiate football players at three time points: before the season, after one season, and after six months of no contact.
- Significant increases in diffusion metrics (trace and fractional anisotropy) were observed after one season, indicating potential changes in brain structure due to repetitive head impacts.
- After a six-month no-contact period, these changes appeared to return to baseline levels, suggesting recovery and indicating that breaks from contact play may be beneficial for athletes.
Post-mortem studies reveal a high rate of cavum septi pellucidi (CSP) in chronic traumatic encephalopathy (CTE). It remains, however, to be determined whether or not the presence of CSP may be a potential in vivo imaging marker in populations at high risk to develop CTE. The aim of this study was to evaluate CSP in former professional American football players presenting with cognitive and behavioral symptoms compared with noncontact sports athletes.
View Article and Find Full Text PDFChronic traumatic encephalopathy (CTE) is a neurodegenerative disease confirmed at postmortem. Those at highest risk are professional athletes who participate in contact sports and military personnel who are exposed to repetitive blast events. All neuropathologically confirmed CTE cases, to date, have had a history of repetitive head impacts.
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